Trubnikov G A, Nikulina D M, Gracheva L N, Nikolaeva N N, Sukharev A E
Ter Arkh. 1988;60(12):66-70.
The content of normal serum proteins, acute phase (C-reactive protein, pregnancy-associated alpha 2-glycoprotein) and tissue proteins (ferritin, nonspecific tissue esterase) was studied in the sputum of 256 patients with different pulmonary pathology, over time using immunochemical methods. Protein elimination with the sputum was shown to depend upon the nature and gravity of bronchitis and pulmonary destruction. Analysis of the qualitative composition of the sputum proteins and their content can be used in pulmonology for differential diagnosis and assessment of a course of pulmonary diseases.
采用免疫化学方法，对256例患有不同肺部疾病的患者痰液中正常血清蛋白、急性期蛋白（C反应蛋白、妊娠相关α2-糖蛋白）及组织蛋白（铁蛋白、非特异性组织酯酶）的含量随时间变化情况进行了研究。结果表明，痰液中蛋白质的排出量取决于支气管炎的性质和严重程度以及肺部破坏情况。痰液蛋白质的定性组成及其含量分析可用于肺病学中肺部疾病的鉴别诊断及病情评估。
