Sukharev A E, Trubnikov G A, Nichoga V D
Ter Arkh. 1991;63(12):30-4.
Immunochemical and radioimmunological assays were used to measure the content of ferritin in blood, sputum and pleural fluid in patients with different pathology as well as in tissues of the pathologically altered lungs from patients who had died of chronic nonspecific pulmonary diseases (CNPD) and lung carcinoma. The measurements of ferritin in blood and sputum provide additional possibilities of recognizing the process activity in CNPD and tuberculosis, in differential diagnosis between lung carcinoma and tuberculosis during comprehensive examination of patients. In the pathologically altered lungs, the greatest content of ferritin was discovered in the areas of pneumofibrosis associated with CNPD, in the stromal structures of the cancerous node.
采用免疫化学和放射免疫分析方法,测定了不同病理状态患者血液、痰液和胸液中铁蛋白含量,以及死于慢性非特异性肺部疾病(CNPD)和肺癌患者的病变肺组织中铁蛋白含量。血液和痰液中铁蛋白的测定为认识CNPD和结核病的病情活动、在对患者进行全面检查时鉴别肺癌和结核病提供了更多可能。在病变肺组织中,铁蛋白含量最高的是与CNPD相关的肺纤维化区域以及癌结节的基质结构。