Karunasumetta Chananya, Kuptarnond Chusak, Prathanee Sompop, Intanoo Worawit, Wongbuddha Chawalit
J Med Assoc Thai. 2014 Jan;97(1):52-9.
To study the surgical outcome of congenital lung malformation and natural history of the disease at Srinagarind Hospital.
Retrospectively review the medical records of 25 patients diagnosed with congenital lung malformation who underwent surgical treatment between January 2001 and December 2011.
Twenty-five patients diagnosed with congenital lung malformation underwent surgery: 16 males (64%), 9 females (36%), median age seven months, median body weight 6 kg. Twelve (48%) had congenital cystic adenomatoid malformation congenital cystic adenomatoidmaflormation (CCAM), seven (28%) pulmonary sequestration, four (16%) congenital lobar emphysema, and one a bronchogenic cyst (4%). The most common presenting symptoms were respiratory tract infection (14, 56%), respiratory distress (7, 28%), lung abscess (1, 4%), hemoptysis (1, 40%), and asymptomatic (2, 8%). Post-operative mortality over 30 days was 0. Complications included lung infection, atelectasis, post-operative bleeding, and wound infection. Post-operative follow-up (lasting between 1-8 years) revealed normal tolerance to daily activity without any respiratory problems.
Surgical treatment for congenital lung malformations had a good result with few complications.
研究诗里拉吉医院先天性肺发育畸形的手术治疗效果及该疾病的自然史。
回顾性分析2001年1月至2011年12月间25例诊断为先天性肺发育畸形并接受手术治疗患者的病历资料。
25例诊断为先天性肺发育畸形的患者接受了手术治疗：男性16例（64%），女性9例（36%），中位年龄7个月，中位体重6千克。12例（48%）患有先天性囊性腺瘤样畸形（CCAM），7例（28%）为肺隔离症，4例（16%）为先天性大叶性肺气肿，1例为支气管囊肿（4%）。最常见的症状为呼吸道感染（14例，56%）、呼吸窘迫（7例，28%）、肺脓肿（1例，4%）、咯血（1例，4%）及无症状（2例，8%）。30天以上的术后死亡率为0。并发症包括肺部感染、肺不张、术后出血及伤口感染。术后随访（持续1 - 8年）显示患者对日常活动耐受性正常，无任何呼吸问题。
先天性肺发育畸形的手术治疗效果良好，并发症较少。
