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[念珠菌属在阴道的定植。无症状女性中分离出的菌种频率及描述]

[Vaginal colonization by Candida spp. Frequency and description of the species isolated in asymptomatic women].

作者信息

Solís-Arias Martha Patricia, Moreno-Morales Mónica, Dávalos-Tanaka Mónica, Fernández-Martánez Ramón Felipe, Díaz Flores Oscar, Arenas-Guzmán Roberto

出版信息

Ginecol Obstet Mex. 2014 Jan;82(1):1-8.

PMID:24701855
Abstract

BACKGROUND

During reproductive age 75% of women experience at least one episode of vulvovaginal candidiasis, approximately 6% to 55% of healthy women are asymptomatic carriers. In Mexico there are no current data of the frequency of vaginal colonization by Candida in the general population.

OBJECTIVE

To determine the frequency of the colonization by Candida species in asymptomatic women.

MATERIAL AND METHODS

A descriptive, open, observational, prospective, cross sectional study was carried out in adult women attending the cervical cytology department at Hospital General Dr. Manuel Gea González in Mexico City. The study was conducted from January to May 2013.

RESULTS

There were a total of 150 samples of asymptomatic women between 15 and 77 years (mean 43 years). We obtained positive culture for Candida in 19 samples (12.6 %). 47% of the species corresponded to C. albicans, however, it was isolated other species such as C. krusei in 26%, C. glabrata (21%) and C. tropicalis by 15%.

CONCLUSIONS

Our findings are consistent with data reported in the literature. It is relevant the isolation of non-albicans Candida species. These findings may be caused by an increase of inappropriate therapies.

摘要

背景

在育龄期,75%的女性至少经历过一次外阴阴道念珠菌病发作,约6%至55%的健康女性为无症状携带者。在墨西哥,目前尚无关于普通人群中念珠菌阴道定植频率的数据。

目的

确定无症状女性中念珠菌属定植的频率。

材料与方法

在墨西哥城曼努埃尔·盖亚·冈萨雷斯综合医院宫颈细胞学科室就诊的成年女性中开展了一项描述性、开放性、观察性、前瞻性横断面研究。该研究于2013年1月至5月进行。

结果

共有150例年龄在15至77岁(平均43岁)的无症状女性样本。我们在19个样本(12.6%)中获得了念珠菌阳性培养结果。47%的菌种为白色念珠菌,然而,还分离出了其他菌种,如克柔念珠菌占26%,光滑念珠菌(21%),热带念珠菌占15%。

结论

我们的研究结果与文献报道的数据一致。非白色念珠菌菌种的分离具有相关性。这些发现可能是由于不恰当治疗增加所致。

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引用本文的文献

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Vaginal Candida albicans infections: host-pathogen-microbiome interactions.阴道白色念珠菌感染:宿主-病原体-微生物组相互作用
FEMS Microbiol Rev. 2025 Jan 14;49. doi: 10.1093/femsre/fuaf013.