Cheong Soon Keen, Johannes Pietersen Alexander Nicolaas
ARC Centre of Excellence in Vision Science,The University of Sydney Eye Hospital Campus,Sydney,New South Wales 2001,Australia.
Vis Neurosci. 2014 May;31(3):263-73. doi: 10.1017/S0952523814000066. Epub 2014 Apr 7.
We studied the functional connectivity of cells in the lateral geniculate nucleus (LGN) with the primary visual cortex (V1) in anesthetized marmosets (Callithrix jacchus). The LGN sends signals to V1 along parallel visual pathways called parvocellular (P), magnocellular (M), and koniocellular (K). To better understand how these pathways provide inputs to V1, we antidromically activated relay cells in the LGN by electrically stimulating V1 and measuring the conduction latencies of P (n = 7), M (n = 14), and the "Blue-ON" (n = 5) subgroup of K cells (K-BON cells). We found that the antidromic latencies of K-BON cells were similar to those of P cells. We also measured the response latencies to high contrast visual stimuli for a subset of cells. We found the LGN cells that have the shortest latency of response to visual stimulation also have the shortest antidromic latencies. We conclude that Blue color signals are transmitted directly to V1 from the LGN by K-BON cells.
我们研究了麻醉状态下狨猴（绢毛猴）外侧膝状核（LGN）中的细胞与初级视皮层（V1）之间的功能连接。LGN通过称为小细胞（P）、大细胞（M）和异细胞（K）的平行视觉通路向V1发送信号。为了更好地理解这些通路如何向V1提供输入，我们通过电刺激V1并测量P细胞（n = 7）、M细胞（n = 14）和K细胞的“蓝光开启”（n = 5）亚组（K-BON细胞）的传导潜伏期，对LGN中的中继细胞进行逆向激活。我们发现K-BON细胞的逆向潜伏期与P细胞相似。我们还测量了一部分细胞对高对比度视觉刺激的反应潜伏期。我们发现，对视觉刺激反应潜伏期最短的LGN细胞，其逆向潜伏期也最短。我们得出结论，蓝色信号由K-BON细胞从LGN直接传递至V1。
