Amly Wajd, Chen Chih-Yang, Isa Tadashi
Division of Neurobiology and Physiology, Department of Neuroscience, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Institute for the Advanced Study of Human Biology (WPI-ASHBi), Kyoto University, Kyoto, Japan.
Front Syst Neurosci. 2024 Oct 23;18:1478019. doi: 10.3389/fnsys.2024.1478019. eCollection 2024.
Marmosets are expected to serve as a valuable model for studying the primate visuomotor system due to their similar oculomotor behaviors to humans and macaques. Despite these similarities, differences exist; challenges in training marmosets on tasks requiring suppression of unwanted saccades, having consistently shorter, yet more variable saccade reaction times (SRT) compared to humans and macaques. This study investigates whether the short and variable SRT in marmosets is related to differences in visual signal transduction and variability in inhibitory control. We refined a computational SRT model, adjusting parameters to better capture the marmoset SRT distribution in a gap saccade task. Our findings indicate that visual information processing is faster in marmosets, and that saccadic inhibition is more variable compared to other species.
由于狨猴的眼球运动行为与人类和猕猴相似，它们有望成为研究灵长类动物视觉运动系统的有价值模型。尽管存在这些相似之处，但仍存在差异；在训练狨猴执行需要抑制不必要扫视的任务时存在挑战，与人类和猕猴相比，狨猴的扫视反应时间（SRT）始终更短，但变化更大。本研究调查了狨猴短而可变的SRT是否与视觉信号转导的差异和抑制控制的变异性有关。我们改进了一个计算SRT模型，调整参数以更好地捕捉间隙扫视任务中狨猴的SRT分布。我们的研究结果表明，狨猴的视觉信息处理速度更快，并且与其他物种相比，扫视抑制的变异性更大。
