植物长寿的休眠途径。

A quiescent path to plant longevity.

机构信息

Department of Plant Systems Biology, Vlaams Instituut voor Biotechnologie (VIB), and Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Gent, Belgium.

出版信息

Trends Cell Biol. 2014 Aug;24(8):443-8. doi: 10.1016/j.tcb.2014.03.004. Epub 2014 Apr 3.

DOI:10.1016/j.tcb.2014.03.004

PMID:24704103

Abstract

The giant sequoia and the bristlecone pine trees are capable of living up to several hundreds or even thousands of years. Plants achieve this longevity by regenerating stem cells capable of giving rise to all differentiated cells. Plant stem cells reside in specific niches with high mitotic activity that are known as meristems. Remarkably, at the center of the root stem cell niche (SCN) resides a group of mitotically inactive cells known as the quiescent center (QC). Recent studies suggest that stress-related phytohormones and DNA damage can initiate QC cell division, resulting in the replenishment of stem cells surrounding the QC. We therefore propose that the QC represents a pool of backup cells that serve to replace damaged stem cells, thereby contributing to plant longevity.

摘要

巨杉和狐尾松能活好几百年甚至几千年。植物通过再生能够产生所有分化细胞的干细胞来实现这种长寿。植物干细胞位于具有高有丝分裂活性的特定小生境中，这些小生境被称为分生组织。值得注意的是，在根干细胞小生境（SCN）的中心，有一群有丝分裂不活跃的细胞，被称为静止中心（QC）。最近的研究表明，与应激相关的植物激素和 DNA 损伤可以启动 QC 细胞分裂，从而补充 QC 周围的干细胞。因此，我们提出 QC 代表了一个备用细胞池，用于替代受损的干细胞，从而有助于植物的长寿。