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手术使转移性 Merkel 细胞癌合并 Lambert-Eaton 肌无力综合征患者获得完全缓解。

Surgery results in complete cure of Lambert-Eaton myasthenic syndrome in a patient with metastatic Merkel cell carcinoma.

机构信息

Welsh Centre for Burns and Plastic Surgery, Morriston Hospital, Swansea SA1 6NL, United Kingdom.

Welsh Centre for Burns and Plastic Surgery, Morriston Hospital, Swansea SA1 6NL, United Kingdom; University Hospital of Wales, Heath Park, Cardiff CF14 4XW, United Kingdom.

出版信息

J Plast Reconstr Aesthet Surg. 2014 Jun;67(6):e162-4. doi: 10.1016/j.bjps.2014.03.014. Epub 2014 Mar 21.

Abstract

Lambert-Eaton myasthenic syndrome is a paraneoplastic phenomenon associated with neuroendocrine tumours, most frequently small cell lung carcinoma. Merkel cell carcinoma is a rare cause of Lambert-Eaton myasthenic syndrome. A 70-year old gentleman was referred with metastatic axillary nodal disease from a previously resected Merkel cell carcinoma of the left arm. Pre-operatively, the patient was wheelchair-bound from Lambert-Eaton myasthenic syndrome. Level I-III left axillary node clearance was performed and within 6 months, he had experienced full recovery of muscle power and mobility. We describe a case of complete cure of Lambert-Eaton myasthenic syndrome following axillary nodal clearance in a patient with metastatic Merkel cell carcinoma.

摘要

Lambert-Eaton 肌无力综合征是一种副瘤现象,与神经内分泌肿瘤相关,最常见的是小细胞肺癌。 Merkel 细胞癌是 Lambert-Eaton 肌无力综合征的罕见病因。一位 70 岁的绅士因左手臂先前切除的 Merkel 细胞癌转移至腋窝淋巴结而被转介。术前,患者因 Lambert-Eaton 肌无力综合征而坐轮椅。行 I-III 级左侧腋窝淋巴结清扫术,术后 6 个月内,患者的肌肉力量和活动度完全恢复。我们描述了一例转移性 Merkel 细胞癌患者行腋窝淋巴结清扫术后 Lambert-Eaton 肌无力综合征完全治愈的病例。

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