Welsh Centre for Burns and Plastic Surgery, Morriston Hospital, Swansea SA1 6NL, United Kingdom.
Welsh Centre for Burns and Plastic Surgery, Morriston Hospital, Swansea SA1 6NL, United Kingdom; University Hospital of Wales, Heath Park, Cardiff CF14 4XW, United Kingdom.
J Plast Reconstr Aesthet Surg. 2014 Jun;67(6):e162-4. doi: 10.1016/j.bjps.2014.03.014. Epub 2014 Mar 21.
Lambert-Eaton myasthenic syndrome is a paraneoplastic phenomenon associated with neuroendocrine tumours, most frequently small cell lung carcinoma. Merkel cell carcinoma is a rare cause of Lambert-Eaton myasthenic syndrome. A 70-year old gentleman was referred with metastatic axillary nodal disease from a previously resected Merkel cell carcinoma of the left arm. Pre-operatively, the patient was wheelchair-bound from Lambert-Eaton myasthenic syndrome. Level I-III left axillary node clearance was performed and within 6 months, he had experienced full recovery of muscle power and mobility. We describe a case of complete cure of Lambert-Eaton myasthenic syndrome following axillary nodal clearance in a patient with metastatic Merkel cell carcinoma.
Lambert-Eaton 肌无力综合征是一种副瘤现象，与神经内分泌肿瘤相关，最常见的是小细胞肺癌。 Merkel 细胞癌是 Lambert-Eaton 肌无力综合征的罕见病因。一位 70 岁的绅士因左手臂先前切除的 Merkel 细胞癌转移至腋窝淋巴结而被转介。术前，患者因 Lambert-Eaton 肌无力综合征而坐轮椅。行 I-III 级左侧腋窝淋巴结清扫术，术后 6 个月内，患者的肌肉力量和活动度完全恢复。我们描述了一例转移性 Merkel 细胞癌患者行腋窝淋巴结清扫术后 Lambert-Eaton 肌无力综合征完全治愈的病例。
