Waggaman Christina, Julian Pamela, Niccolai Linda M
Yale School of Public Health, Department of Epidemiology of Microbial Diseases, 60 College Street, New Haven, CT 06520, USA.
Yale School of Public Health, Connecticut Emerging Infections Program, One Church Street, New Haven, CT 06520, USA.
Cancer Epidemiol. 2014 Jun;38(3):248-52. doi: 10.1016/j.canep.2014.03.004. Epub 2014 Apr 4.
We estimated the main and interactive effects of individual race/ethnicity (black, Hispanic, white) and area race, ethnicity, and poverty (proportions of the female population black, Hispanic, and living below the federal poverty level at the census tract level, respectively) on rates of high-grade cervical lesions among young women. Using data from a statewide surveillance system during 2008-2011, we found a marginally significant interaction (P<0.05) between individual race/ethnicity and area race, with black and Hispanic women living in areas with ≥20% of the female population black having elevated rates compared to those living in areas with <20% of the female population black. These findings indicate a possible synergistic effect between individual race/ethnicity and racial composition in neighborhoods on precancerous cervical lesions.
我们评估了个体种族/族裔（黑人、西班牙裔、白人）以及地区种族、族裔和贫困状况（分别为普查区层面黑人、西班牙裔女性人口以及生活在联邦贫困线以下的女性人口的比例）对年轻女性高级别宫颈病变发生率的主要影响和交互作用。利用2008 - 2011年全州监测系统的数据，我们发现个体种族/族裔与地区种族之间存在边缘显著的交互作用（P<0.05），与生活在黑人女性人口比例低于20%地区的女性相比，生活在黑人女性人口比例≥20%地区的黑人和西班牙裔女性发病率升高。这些发现表明个体种族/族裔与社区种族构成之间可能对宫颈癌前病变存在协同效应。
