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肌钙蛋白升高的非缺血性原因。

A non-ischaemic cause of elevated troponin.

作者信息

Lefort Guy, D'Antonio Claude, Caffery Terrell

机构信息

Department of Emergency Medicine, LSU Health Baton Rouge, Baton Rouge, Louisiana, USA.

出版信息

BMJ Case Rep. 2014 Apr 4;2014:bcr2014203729. doi: 10.1136/bcr-2014-203729.

DOI:10.1136/bcr-2014-203729
PMID:24706705
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3987630/
Abstract

A 27-year-old woman with chest pain was admitted for elevated troponin levels. Troponin remained mildly elevated upon repeat testing, and a review of the medical record revealed that she had had an elevated troponin level in the past. She had a cardiac catheterisation that revealed angiographically normal coronary arteries. Repeat troponin testing with and without ethylene glycol revealed a negative troponin level after addition of ethylene glycol, suggesting antibodies were interfering with the assay.

摘要

一名27岁胸痛女性因肌钙蛋白水平升高入院。复查时肌钙蛋白仍轻度升高,查阅病历发现她过去肌钙蛋白水平也曾升高。她接受了心脏导管检查,血管造影显示冠状动脉正常。在添加和不添加乙二醇的情况下重复检测肌钙蛋白,添加乙二醇后肌钙蛋白水平呈阴性,提示抗体干扰了检测。

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本文引用的文献

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Diagnostic indicators of non-cardiovascular chest pain: a systematic review and meta-analysis.非心血管胸痛的诊断指标:系统评价和荟萃分析。
BMC Med. 2013 Nov 8;11:239. doi: 10.1186/1741-7015-11-239.
2
The independent association of anxiety with non-cardiac chest pain.焦虑与非心源性胸痛的独立相关性。
Psychol Health. 2014;29(3):253-63. doi: 10.1080/08870446.2013.843681. Epub 2013 Oct 28.
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Are troponin assays occasionally deceiving us?肌钙蛋白检测偶尔会欺骗我们吗?
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False positive cardiac troponin elevation due to heterophile antibodies: more common than we recognise?嗜异性抗体导致的心肌肌钙蛋白假阳性升高:是否比我们认为的更常见?
BMJ Case Rep. 2010 Jul 15;2010:bcr1120092477. doi: 10.1136/bcr.11.2009.2477.
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A non-coronary syndrome cause of elevated troponin.肌钙蛋白升高的非冠状动脉综合征病因。
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Noncardiac chest pain: epidemiology, natural course and pathogenesis.非心源性胸痛:流行病学、自然病程和发病机制。
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Clin Chem Lab Med. 2011 May;49(5):923-5. doi: 10.1515/CCLM.2011.147. Epub 2011 Mar 10.
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