Osada Hiroaki, Marui Akira, Tanaka Shiro, Meshii Katsuaki, Ohnaka Motoaki, Nakajima Hiroyuki
Department of Cardiovascular Surgery, Mitsubishi Kyoto Hospital, Kyoto, Japan
Department of Cardiovascular Surgery/Translational Research Center, Kyoto University Hospital, Kyoto, Japan.
Asian Cardiovasc Thorac Ann. 2015 Jan;23(1):24-30. doi: 10.1177/0218492314531138. Epub 2014 Apr 4.
Acute subdural hematoma is uncommon following open-heart surgery, but may result in increased mortality and morbidity.
A retrospective analysis was performed involving all patients who underwent thoracic aortic surgery from January 2009 to February 2013. There were 53 patients who had thoracic aortic repair with open distal anastomosis and required selective cerebral perfusion with or without retrograde cerebral perfusion. We evaluated the incidence of postoperative acute subdural hematoma. The patients were divided into two groups: a subdural hematoma group who had symptomatic subdural hematoma postoperatively, and a non-subdural hematoma group who had no subdural hematoma. The variables were compared between the 2 groups.
Eight (15.1%) patients had a transient symptomatic subdural hematoma; none required surgical evacuation of the hematoma. There were significant differences between the two groups in terms mean and maximum retrograde cerebral perfusion flow, and the volume of intraoperative platelet transfusion. Multivariate analysis revealed that a significant risk factor for acute subdural hematoma following thoracic aortic surgery was the amount of intraoperative platelet transfusion (odds ratio = 0.9, 95% confidence interval: 0.81-0.98, p = 0.015).
This retrospective study demonstrated that the subdural hematoma group received fewer units of platelets, thus it appears to be important to give platelets appropriately. Strict flow regulation or avoidance of retrograde cerebral perfusion is suggested.
心脏直视手术后急性硬膜下血肿并不常见,但可能导致死亡率和发病率增加。
对2009年1月至2013年2月期间接受胸主动脉手术的所有患者进行回顾性分析。有53例患者接受了开放远端吻合的胸主动脉修复术,需要进行选择性脑灌注,无论是否进行逆行脑灌注。我们评估了术后急性硬膜下血肿的发生率。患者分为两组:术后有症状性硬膜下血肿的硬膜下血肿组和无硬膜下血肿的非硬膜下血肿组。比较两组之间的变量。
8例(15.1%)患者出现短暂性症状性硬膜下血肿;均无需手术清除血肿。两组在平均和最大逆行脑灌注流量以及术中血小板输注量方面存在显著差异。多因素分析显示,胸主动脉手术后急性硬膜下血肿的一个重要危险因素是术中血小板输注量(比值比=0.9,95%置信区间:0.81-0.98,p=0.015)。
这项回顾性研究表明,硬膜下血肿组输注的血小板单位较少,因此适当输注血小板似乎很重要。建议严格控制流量或避免逆行脑灌注。