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心包膜外脂肪坏死:一种被低估的病症。

Epipericardial fat necrosis: an underdiagnosed condition.

机构信息

Radiology Division, Hospital Sírio-Libanês, São Paulo, Brazil.

出版信息

Br J Radiol. 2014 Jun;87(1038):20140118. doi: 10.1259/bjr.20140118. Epub 2014 Apr 8.

Abstract

OBJECTIVE

Epipericardial fat necrosis (EFN) is an uncommon benign and self-limited condition that leads patients to the emergency department (ED) owing to the onset of acute pleuritic chest pain. The aim of this study was to describe the cases of this disease in our institution and to illustrate the associated clinical and radiological findings.

METHODS

We reviewed 3604 chest scans referred by the ED from November 2011 to July 2013. Patients diagnosed with epipericardial necrosis had their medical records and original tomography reports analysed.

RESULTS

Chest pain was the primary complaint in 426 patients; 11 of them had definitive EFN findings characterized by a round soft-tissue attenuation lesion with a varying degree of strands. All patients presented with pleuritic chest pain on the same side as the lesion. Pericardial thickening, pleural effusion and mild atelectasis were the associated tomography findings. Cardiac enzyme and D-dimer tests performed during the episode were normal in all cases. 27% of the cases only were correctly diagnosed with EFN at the time of presentation.

CONCLUSION

EFN is a benign inflammatory condition frequently overlooked in the ED by physicians and radiologists but is an important factor in the differential diagnosis of patients with acute chest pain.

ADVANCES IN KNOWLEDGE

The article adds clinically and radiologically useful information about the condition and displays the importance of making the correct diagnosis to avoid unnecessary examinations.

摘要

目的

心包外脂肪坏死(EFN)是一种罕见的良性、自限性疾病,可导致患者因突发胸痛而到急诊科就诊。本研究旨在描述本机构中该疾病的病例,并说明其相关的临床和影像学发现。

方法

我们回顾了 2011 年 11 月至 2013 年 7 月间由急诊科转介的 3604 例胸部扫描。对诊断为心包外脂肪坏死的患者进行了病历和原始断层扫描报告分析。

结果

胸痛是 426 例患者的主要主诉;其中 11 例有明确的 EFN 发现,表现为圆形软组织衰减病变,伴有不同程度的条索状。所有患者均表现为病变同侧的胸膜炎性胸痛。心包增厚、胸腔积液和轻度肺不张是相关的断层扫描发现。在发作期间进行的心肌酶和 D-二聚体检查在所有病例中均正常。27%的病例在就诊时仅被正确诊断为 EFN。

结论

EFN 是一种良性炎症性疾病,常被急诊科医生和放射科医生忽视,但在急性胸痛患者的鉴别诊断中是一个重要因素。

知识进展

本文增加了有关该疾病的临床和影像学有用信息,并显示了做出正确诊断以避免不必要检查的重要性。

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