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新冠病毒感染后的心外膜脂肪坏死:一例报告

Epicardial Fat Necrosis After COVID-19 Infection: A Case Report.

作者信息

Zayour Mohamad, Karaki Mahmoud, Al Ashkar Rana, Chammas Elie

机构信息

Cardiology, University of Balamand, Beirut, LBN.

Diabetes and Endocrinology, University of Balamand, Beirut, LBN.

出版信息

Cureus. 2022 May 20;14(5):e25154. doi: 10.7759/cureus.25154. eCollection 2022 May.

DOI:10.7759/cureus.25154
PMID:35746997
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9206713/
Abstract

Epipericardial or epicardial fat necrosis (EFN) is a self-limited inflammatory process occurring in the mediastinal fat surrounding the heart. It is an uncommon cause of acute chest pain and mimics more critical clinical disorders such as acute coronary syndrome, aortic dissection, and pulmonary embolism. However, EFN is frequently overlooked and under-recognized in emergency departments (EDs) owing to the unfamiliarity of this condition among physicians and radiologists. Herein, we present the case of a previously healthy young male patient, with a recent history of mild COVID-19 infection (two weeks before presentation), who presented to the ED for acute chest pain. Paraclinical evaluation including computed tomography (CT) of the chest revealed fat stranding along with the left epicardial fat pad in favor of EFN.

摘要

心包外或心外膜脂肪坏死(EFN)是一种发生在心脏周围纵隔脂肪中的自限性炎症过程。它是急性胸痛的罕见原因,可模拟更严重的临床疾病,如急性冠状动脉综合征、主动脉夹层和肺栓塞。然而,由于急诊科医生和放射科医生对这种疾病不熟悉,EFN在急诊科经常被忽视和认识不足。在此,我们报告一例既往健康的年轻男性患者,近期有轻度新冠病毒感染史(就诊前两周),因急性胸痛就诊于急诊科。包括胸部计算机断层扫描(CT)在内的辅助检查显示左心外膜脂肪垫处有脂肪条索,支持EFN的诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a931/9206713/cd641265f08a/cureus-0014-00000025154-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a931/9206713/e0eae3134126/cureus-0014-00000025154-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a931/9206713/f16ccbb36dcb/cureus-0014-00000025154-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a931/9206713/d3164f032aaa/cureus-0014-00000025154-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a931/9206713/cd641265f08a/cureus-0014-00000025154-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a931/9206713/e0eae3134126/cureus-0014-00000025154-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a931/9206713/f16ccbb36dcb/cureus-0014-00000025154-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a931/9206713/d3164f032aaa/cureus-0014-00000025154-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a931/9206713/cd641265f08a/cureus-0014-00000025154-i04.jpg

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引用本文的文献

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本文引用的文献

1
Case report: epipericardial fat necrosis-a rare cause of chest pain.病例报告:心包外脂肪坏死——胸痛的罕见病因。
Eur Heart J Case Rep. 2021 Dec 31;6(1):ytab529. doi: 10.1093/ehjcr/ytab529. eCollection 2022 Jan.
2
Epipericardial Fat Necrosis: A Concise Review of Literature.心包外脂肪坏死:文献综述
Cureus. 2021 Feb 3;13(2):e13106. doi: 10.7759/cureus.13106.
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Epicardial adipose tissue: fuel for COVID-19-induced cardiac injury?心外膜脂肪组织:是新冠病毒诱导的心脏损伤的“燃料”吗?
Eur Heart J. 2020 Jun 21;41(24):2334-2335. doi: 10.1093/eurheartj/ehaa474.
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The Variety of Cardiovascular Presentations of COVID-19.新型冠状病毒肺炎的心血管表现多样性
Circulation. 2020 Jun 9;141(23):1930-1936. doi: 10.1161/CIRCULATIONAHA.120.047164. Epub 2020 Apr 3.
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Epipericardial fat necrosis as cause of chest pain in patient after heart transplantation.心脏移植术后患者胸痛的病因:心包膜脂肪坏死。
Am J Transplant. 2020 May;20(5):1451-1453. doi: 10.1111/ajt.15744. Epub 2020 Jan 24.
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Fat necrosis in the Breast: A systematic review of clinical.乳房脂肪坏死:临床的系统评价。
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Epipericardial fat necrosis as a cause of acute chest pain.心包外脂肪坏死作为急性胸痛的一个病因
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Epipericardial Fat Necrosis: Who Should Be a Candidate?心包外脂肪坏死:谁应成为候选对象?
AJR Am J Roentgenol. 2016 Oct;207(4):773-777. doi: 10.2214/AJR.15.15934. Epub 2016 Jun 28.
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Epipericardial fat necrosis: an underdiagnosed condition.心包膜外脂肪坏死:一种被低估的病症。
Br J Radiol. 2014 Jun;87(1038):20140118. doi: 10.1259/bjr.20140118. Epub 2014 Apr 8.
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Imaging manifestations of mediastinal fat necrosis.
Case Rep Radiol. 2013;2013:323579. doi: 10.1155/2013/323579. Epub 2013 Nov 28.