Moghazy Dalia, Al-Hendy Omar, Al-Hendy Ayman
Center for Women Health Research, Meharry Medical College, Nashville, Tennessee, USA.
J Ovarian Res. 2014 Apr 7;7:36. doi: 10.1186/1757-2215-7-36.
A Krukenberg tumor is a rare and potentially deadly cause of elevated serum β-hCG as part of a paraneoplastic syndrome. This study aims to describe the unusual case of a 36-year-old woman that presented to the Emergency Department (ED) with back pain and a positive urine pregnancy test. Assessment revealed no intrauterine pregnancy and a small left ovarian cyst. Further investigation showed moderately differentiated gastric adenocarcinoma with distant metastases to the spine. The patient died less than 3 months after her first presentation to the ED. Paraneoplastic syndrome, albeit rare, should be considered in the differential diagnosis of elevated β-hCG due to the high mortality associated with Krukenberg tumors.
库肯勃瘤是一种罕见且可能致命的血清β-人绒毛膜促性腺激素升高的原因,属于副肿瘤综合征的一部分。本研究旨在描述一名36岁女性的罕见病例,该患者因背痛到急诊科就诊,尿妊娠试验呈阳性。评估显示宫内未孕,左侧有一个小卵巢囊肿。进一步检查发现为中度分化的胃腺癌,并伴有脊柱远处转移。该患者在首次到急诊科就诊后不到3个月就去世了。尽管副肿瘤综合征罕见,但由于库肯勃瘤相关的高死亡率,在β-人绒毛膜促性腺激素升高的鉴别诊断中应考虑该综合征。