Sood Neelam, Rewri Shivani, Nigam Jitendra Singh
Department of Pathology, D.D.U. Hospital , Harinagar, New Delhi, India.
Rare Tumors. 2014 Jan 29;6(1):5029. doi: 10.4081/rt.2014.5029. eCollection 2014 Jan 23.
Extraskeletal osteosarcoma is a rare malignant mesenchymal neoplasm and its small cell variant is one among the rarest variant. This article describes a 60-year-old woman presenting with a large, lobulated, painful mass in left thigh with associated history of trauma since 18 months. Her magnetic resonance imaging showed a variegated mixed intensity lesion with associated cystic degeneration, necrosis and matrix arborizing nearby muscles. Fine needle aspiration cytology showed a small cell lesion with very scant osteoid. Tumor was excised and histopathological diagnosis was small cell osteosarcoma involving adjacent muscles and fat with sparing of lymph nodes. The aim of this article is to present the clinical, radiological, cyto-histological and immunohistochemical features of this extremely rare lesion.
骨外骨肉瘤是一种罕见的恶性间叶性肿瘤，其小细胞变异型是最罕见的变异型之一。本文描述了一名60岁女性，自18个月前起左大腿出现一个大的、分叶状、疼痛性肿块，并伴有外伤史。她的磁共振成像显示为一个杂色混合强度病变，伴有囊性退变、坏死，且基质在附近肌肉呈树枝状分布。细针穿刺细胞学检查显示为一个小细胞病变，骨样组织极少。肿瘤被切除，组织病理学诊断为小细胞骨肉瘤，累及相邻肌肉和脂肪，未累及淋巴结。本文旨在介绍这种极其罕见病变的临床、放射学、细胞组织学和免疫组化特征。
