Zuo Zhiwei, MacMillan David W C
Merck Center for Catalysis, Princeton University , Princeton, New Jersey 08544, United States.
J Am Chem Soc. 2014 Apr 9;136(14):5257-60. doi: 10.1021/ja501621q. Epub 2014 Mar 31.
The direct decarboxylative arylation of α-amino acids has been achieved via visible light-mediated photoredox catalysis. This method offers rapid entry to prevalent benzylic amine architectures from an abundant biomass, specifically α-amino acid precursors. Significant substrate scope is observed with respect to both the amino acid and arene components.
通过可见光介导的光氧化还原催化实现了α-氨基酸的直接脱羧芳基化反应。该方法能够从丰富的生物质（特别是α-氨基酸前体）快速构建常见的苄胺结构。在氨基酸和芳烃组分方面都观察到了显著的底物范围。
