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[心脏瓣膜手术的适应证和时机——欧洲指南总结]

[Indication and timing of heart valve surgery - summery of the European guidelines].

作者信息

Sündermann Simon H, Reser Diana, Czerny Martin, Falk Volkmar

机构信息

Klinik für Herz- und Gefässchirurgie, Universitätsspital Zürich.

出版信息

Praxis (Bern 1994). 2014 Apr 9;103(8):445-51. doi: 10.1024/1661-8157/a001626.

DOI:10.1024/1661-8157/a001626
PMID:24713380
Abstract

Most common heart valve diseases in western industrialized nations are the aortic valve stenosis and the mitral valve regurgitation. More seldom are a regurgitation of the aortic valve and mitral valve stenosis. Even more seldom are heart valve diseases of the Tricuspid and the pulmonary valve. The only curative therapy in severe heart valve disease is a surgical intervention. The timing is crucial for the outcome. Especially in asymptomatic patients it's difficult to find the right point of time for intervention due to missing realization of the health status. In 2013, the European Association for Cardio-Thoracic Surgery (EACTS) and the European Society of Cardiology (ESC) published guidelines according to the therapy in heart valve disease. Here we want to summarize the recommendations of these guidelines in regards of timing of the surgical intervention.

摘要

在西方工业化国家,最常见的心脏瓣膜疾病是主动脉瓣狭窄和二尖瓣反流。主动脉瓣反流和二尖瓣狭窄则较为少见。三尖瓣和肺动脉瓣的心脏瓣膜疾病更为罕见。严重心脏瓣膜疾病的唯一治愈性疗法是手术干预。时机对于治疗结果至关重要。尤其是在无症状患者中,由于对健康状况认识不足,很难找到合适的干预时机。2013年,欧洲心胸外科学会(EACTS)和欧洲心脏病学会(ESC)发布了关于心脏瓣膜疾病治疗的指南。在此,我们想总结这些指南中关于手术干预时机的建议。

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Optical coherence tomography and multiphoton microscopy offer new options for the quantification of fibrotic aortic valve disease in ApoE mice.光学相干断层扫描和多光子显微镜为 ApoE 小鼠纤维化主动脉瓣疾病的定量分析提供了新的选择。
Sci Rep. 2021 Mar 12;11(1):5834. doi: 10.1038/s41598-021-85142-4.
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Ex vivo 4D visualization of aortic valve dynamics in a murine model with optical coherence tomography.利用光学相干断层扫描对小鼠模型主动脉瓣动力学进行体外4D可视化。
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