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壶腹腺癌中的纵隔淋巴结肿大:并非总是转移性的。

Mediastinal lymphadenopathy in ampullary adenocarcinoma: not always metastatic.

作者信息

Rao Chalapathi A S, Rana Surinder S, Bhasin Deepak K, Nada Ritambhra, Sampath Santosh, Mittal Bhagwant R, Sharma Vishal, Dhaliwal Harpal S, Singh Kartar

机构信息

Department of Gastroenterology (Chalapathi A.S. Rao, Surinder S. Rana, Deepak K. Bhasin, Vishal Sharma, Harpal S. Dhaliwal, Kartar Singh).

Histopathology Department (Ritambhra Nada).

出版信息

Ann Gastroenterol. 2012;25(2):167-169.

PMID:24714280
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3959392/
Abstract

Malignancies can metastasize through hematogenous or lymphatic routes. Enlarged lymph nodes in a known case of malignancy do not always imply metastasis. A middle-aged female patient presented to us with abdominal pain and jaundice. Investigation revealed ampullary growth due to adenocarcinoma. Positron emission tomography-computerized tomography scan revealed uptake of the tracer in the ampullary region as well as in enlarged mediastinal lymph nodes. Endoscopic ultrasound-guided fine needle aspiration cytology of the mediastinal lymphadenopathy revealed it to be tuberculous. Mere radiologic evidence of a distant nodal spread must not be regarded as final evidence and obtaining a tissue diagnosis should be strongly considered, as potentially curative therapy may be offered.

摘要

恶性肿瘤可通过血行或淋巴途径转移。在已知恶性肿瘤病例中,肿大的淋巴结并不总是意味着发生了转移。一名中年女性患者因腹痛和黄疸前来就诊。检查发现是壶腹腺癌。正电子发射断层扫描-计算机断层扫描显示示踪剂在壶腹区域以及肿大的纵隔淋巴结中摄取。纵隔淋巴结肿大的内镜超声引导下细针穿刺细胞学检查显示为结核。仅仅影像学上远处淋巴结转移的证据不应被视为最终证据,应强烈考虑进行组织诊断,因为可能会提供潜在的治愈性治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed92/3959392/d7ad5e22217a/AnnGastroenterol-25-167-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed92/3959392/3d66b3ea82f7/AnnGastroenterol-25-167-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed92/3959392/c2594edfee5c/AnnGastroenterol-25-167-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed92/3959392/b03445430e69/AnnGastroenterol-25-167-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed92/3959392/aff5f02bd622/AnnGastroenterol-25-167-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed92/3959392/d7ad5e22217a/AnnGastroenterol-25-167-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed92/3959392/3d66b3ea82f7/AnnGastroenterol-25-167-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed92/3959392/c2594edfee5c/AnnGastroenterol-25-167-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed92/3959392/b03445430e69/AnnGastroenterol-25-167-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed92/3959392/aff5f02bd622/AnnGastroenterol-25-167-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed92/3959392/d7ad5e22217a/AnnGastroenterol-25-167-g005.jpg

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本文引用的文献

1
Endoscopic ultrasound (EUS) features of mediastinal tubercular lymphadenopathy.纵隔结核性淋巴结病的内镜超声(EUS)特征
Hepatogastroenterology. 2011 May-Jun;58(107-108):819-23.
2
Evaluation of mediastinal lymph nodes using F-FDG PET-CT scan and its histopathologic correlation.评估纵隔淋巴结使用 F-FDG PET-CT 扫描及其组织病理学相关性。
Ann Thorac Med. 2011 Jan;6(1):11-6. doi: 10.4103/1817-1737.74270.
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Tuberculosis and malignancy.结核病与恶性肿瘤。
QJM. 2010 Jul;103(7):461-87. doi: 10.1093/qjmed/hcq068. Epub 2010 May 26.
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Biliary strictures secondary to tuberculosis and early ampullary carcinoma.继发于结核和早期壶腹癌的胆管狭窄。
Singapore Med J. 2009 Mar;50(3):e94-6.
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Tumors of the ampulla of vater: histopathologic classification and predictors of survival.Vater壶腹肿瘤:组织病理学分类及生存预测因素
J Am Coll Surg. 2008 Aug;207(2):210-8. doi: 10.1016/j.jamcollsurg.2008.01.028. Epub 2008 May 5.
6
Diagnosis of biliary tract and ampullary carcinomas.胆管癌和壶腹癌的诊断。
J Hepatobiliary Pancreat Surg. 2008;15(1):31-40. doi: 10.1007/s00534-007-1278-6. Epub 2008 Feb 16.
7
Is resection of periampullary or pancreatic adenocarcinoma with synchronous hepatic metastasis justified?对于伴有同步肝转移的壶腹周围癌或胰腺癌进行切除是否合理?
Cancer. 2007 Dec 1;110(11):2484-92. doi: 10.1002/cncr.23074.
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Long-term results of surgical treatment of Vater's ampulla neoplasms.壶腹肿瘤手术治疗的长期结果。
Hepatogastroenterology. 2007 Jun;54(76):1239-42.
9
The maximum standardized uptake values on integrated FDG-PET/CT is useful in differentiating benign from malignant pulmonary nodules.整合的氟代脱氧葡萄糖正电子发射断层显像/计算机断层扫描(FDG-PET/CT)上的最大标准化摄取值有助于鉴别肺结节的良恶性。
Ann Thorac Surg. 2006 Sep;82(3):1016-20. doi: 10.1016/j.athoracsur.2006.03.095.
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Am J Surg. 2006 Jun;191(6):743-8. doi: 10.1016/j.amjsurg.2005.03.042.