Lowery Ryan P, Joy Jordan M, Rathmacher John A, Baier Shawn M, Fuller John C, Shelley Mack C, Jäger Ralf, Purpura Martin, Wilson Stephanie M C, Wilson Jacob M
1Department of Health Sciences and Human Performance, The University of Tampa, Tampa, Florida; 2Metabolic Technologies, Inc., Iowa State University Research Park, Ames, Iowa; 3Department of Animal Science, Iowa State University, Ames, Iowa; 4Department of Statistics, Iowa State University, Ames, Iowa; 5Increnovo LLC, 2138 E Lafayette Pl, Milwaukee, Wisconsin; and 6Department of Nutrition, IMG Academy, Bradenton, Florida.
J Strength Cond Res. 2016 Jul;30(7):1843-54. doi: 10.1519/JSC.0000000000000482.
Lowery, RP, Joy, JM, Rathmacher, JA, Baier, SM, Fuller, JC Jr, Shelley, MC II, Jäger, R, Purpura, M, Wilson, SMC, and Wilson, JM. Interaction of beta-hydroxy-beta-methylbutyrate free acid and adenosine triphosphate on muscle mass, strength, and power in resistance trained individuals. J Strength Cond Res 30(7): 1843-1854, 2016-Adenosine-5'-triphosphate (ATP) supplementation helps maintain performance under high fatiguing contractions and with greater fatigue recovery demands also increase. Current evidence suggests that the free acid form of β-hydroxy-β-methylbutyrate (HMB-FA) acts by speeding regenerative capacity of skeletal muscle after high-intensity or prolonged exercise. Therefore, we investigated the effects of 12 weeks of HMB-FA (3 g) and ATP (400 mg) administration on lean body mass (LBM), strength, and power in trained individuals. A 3-phase double-blind, placebo-, and diet-controlled study was conducted. Phases consisted of an 8-week periodized resistance training program (phase 1), followed by a 2-week overreaching cycle (phase 2), and a 2-week taper (phase 3). Lean body mass was increased by a combination of HMB-FA/ATP by 12.7% (p < 0.001). In a similar fashion, strength gains after training were increased in HMB-FA/ATP-supplemented subjects by 23.5% (p < 0.001). Vertical jump and Wingate power were increased in the HMB-FA/ATP-supplemented group compared with the placebo-supplemented group, and the 12-week increases were 21.5 and 23.7%, respectively. During the overreaching cycle, strength and power declined in the placebo group (4.3-5.7%), whereas supplementation with HMB-FA/ATP resulted in continued strength gains (1.3%). In conclusion, HMB-FA and ATP in combination with resistance exercise training enhanced LBM, power, and strength. In addition, HMB-FA plus ATP blunted the typical response to overreaching, resulting in a further increase in strength during that period. It seems that the combination of HMB-FA/ATP could benefit those who continuously train at high levels such as elite athletes or military personnel.
洛厄里、RP、乔伊、JM、拉特马赫、JA、拜尔、SM、富勒、JC Jr、雪莱、MC II、耶格尔、R、普尔普拉、M、威尔逊、SMC以及威尔逊、JM。β-羟基-β-甲基丁酸游离酸与三磷酸腺苷对阻力训练个体肌肉质量、力量和功率的相互作用。《力量与体能研究杂志》30(7): 1843 - 1854，2016年 - 补充三磷酸腺苷（ATP）有助于在高强度疲劳收缩以及疲劳恢复需求增加的情况下维持运动表现。目前的证据表明，β-羟基-β-甲基丁酸（HMB - FA）的游离酸形式通过加快高强度或长时间运动后骨骼肌的再生能力发挥作用。因此，我们研究了12周给予HMB - FA（3克）和ATP（400毫克）对训练有素个体的瘦体重（LBM）、力量和功率的影响。进行了一项为期3个阶段的双盲、安慰剂和饮食控制研究。各阶段包括一个为期8周的周期性阻力训练计划（第1阶段），随后是一个为期2周的过度训练周期（第2阶段），以及一个为期2周的减量期（第3阶段）。HMB - FA/ATP联合使用使瘦体重增加了12.7%（p < 0.001）。同样，补充HMB - FA/ATP的受试者训练后的力量增长提高了23.5%（p < 0.001）。与补充安慰剂的组相比，补充HMB - FA/ATP的组垂直纵跳和温盖特功率增加，12周的增幅分别为21.5%和23.7%。在过度训练周期中，安慰剂组的力量和功率下降（4.3 - 5.7%），而补充HMB - FA/ATP导致力量持续增加（1.3%）。总之，HMB - FA和ATP与阻力运动训练相结合可增强瘦体重、功率和力量。此外，HMB - FA加ATP减弱了对过度训练的典型反应，导致在此期间力量进一步增加。似乎HMB - FA/ATP的组合可能使那些持续进行高水平训练的人受益，如精英运动员或军事人员。
