Sashidharan Palankezhe, Matele Apoorva, Matele Usha, Al Felahi Nowfel, Kassem Khalid F
Department of General Surgery, Nizwa Hospital, Sultanate of Oman.
Department of Radiology, Nizwa Hospital, Sultanate of Oman.
Oman Med J. 2014 Mar;29(2):138-41. doi: 10.5001/omj.2014.34.
Advances in the identification of gastrointestinal stromal tumors, its molecular and immunohiostochemical basis, and its management have been a watershed in the treatment of gastrointestinal tumors. This paradigm shift occurred over the last two decades and gastrointestinal stromal tumors have now come to be understood as rare gastrointestinal tract tumors with predictable behavior and outcome, replacing the older terminologies like leiomyoma, schwannoma or leiomyosarcoma. This report presents a case of gastric gastrointestinal stromal tumor operated recently in a 47-year-old female patient and the outcome, as well as literature review of the pathological identification, sites of origin, and factors predicting its behavior, prognosis and treatment.
胃肠道间质瘤的识别、其分子和免疫组织化学基础以及治疗方面的进展,已成为胃肠道肿瘤治疗的一个分水岭。这种范式转变发生在过去二十年中,胃肠道间质瘤现在已被理解为具有可预测行为和转归的罕见胃肠道肿瘤,取代了诸如平滑肌瘤、神经鞘瘤或平滑肌肉瘤等旧术语。本报告介绍了一名47岁女性患者近期接受手术的胃胃肠道间质瘤病例及其转归,以及对其病理识别、起源部位和预测其行为、预后及治疗的因素的文献综述。