Sran Sisira, Sran Manpreet, Ferguson Nicole, Anand Prachi
Department of Medicine, Nassau University Medical Center, 2201 Hempstead Turnpike, East Meadow, NY 11554, USA.
New York Institute of Technology, College of Osteopathic Medicine, Northern Boulevard, P.O. Box 8000, Old Westbury, NY 11568-8000, USA ; New York Institute of Technology, College of Osteopathic Medicine, Nassau University Medical Center, East Meadow, NY 11554, USA.
Case Rep Endocrinol. 2014;2014:175029. doi: 10.1155/2014/175029. Epub 2014 Mar 10.
We report a case of sudden thigh pain from spontaneous quadriceps necrosis, also known as diabetic myonecrosis, in a 28-year-old patient with poorly controlled diabetes mellitus. Diabetic muscle infarction is a rare end-organ complication seen in patients with poor glycemic control and advanced chronic microvascular complications. Proposed mechanisms involve atherosclerotic microvascular occlusion, ischemia-reperfusion related injury, vasculitis with microthrombi formation, and an acquired antiphospholipid syndrome. Diabetic myonecrosis most commonly presents as sudden thigh pain with swelling and should be considered in any patient who has poorly controlled diabetes mellitus.
我们报告一例28岁血糖控制不佳的糖尿病患者因自发性股四头肌坏死（也称为糖尿病性肌坏死）而突发大腿疼痛的病例。糖尿病性肌肉梗死是血糖控制不佳和晚期慢性微血管并发症患者中罕见的终末器官并发症。提出的机制包括动脉粥样硬化性微血管闭塞、缺血再灌注相关损伤、伴有微血栓形成的血管炎以及获得性抗磷脂综合征。糖尿病性肌坏死最常见的表现是突发大腿疼痛伴肿胀，对于任何血糖控制不佳的糖尿病患者都应考虑该病。
