Section of Pediatric Pulmonology.
Respir Care. 2013 Oct;58(10):e123-5. doi: 10.4187/respcare.02299. Epub 2013 Jan 29.
Cystic fibrosis (CF) related diabetes is an increasingly common comorbidity in CF patients, with scarce data on end-stage complications in the CF population. We report the case of a 32-year-old with poorly controlled diabetes presenting with sub-acute leg pain and focal quadriceps tenderness. Neuromuscular testing and extensive workup revealed diabetic myonecrosis. To our knowledge, this is the first reported case of diabetic myonecrosis in a patient with CF, and highlights the need for pulmonary physicians to recognize this diabetic complication in CF patients, which is associated with a poor long-term prognosis and existing microvascular complications.
囊性纤维化(CF)相关糖尿病是 CF 患者日益常见的合并症,但 CF 人群中终末期并发症的数据很少。我们报告了一例 32 岁糖尿病控制不佳的患者,表现为亚急性腿部疼痛和股四头肌局限性压痛。神经肌肉测试和广泛的检查显示糖尿病性肌坏死。据我们所知,这是首例 CF 患者糖尿病性肌坏死的报告,强调了肺科医生需要在 CF 患者中识别这种糖尿病并发症的重要性,因为这与较差的长期预后和现有的微血管并发症有关。