Bhatt Geetika, Bhatt Aashish, Dragun Anthony E, Li Xiao-Feng, Civelek A Cahid
Department of Internal Medicine, University of Louisville, 530 S. Jackson Street, Louisville, KY 40202, USA.
Department of Radiation Oncology, The Ohio State University, 300 W 10th Avenue, Columbus, OH 43210, USA.
Case Rep Oncol Med. 2014;2014:281812. doi: 10.1155/2014/281812. Epub 2014 Jan 30.
Osteonecrosis of the jaw is usually a potential complication of bisphosphonate therapy. In a cancer patient, this disease entity can be misdiagnosed as a metastatic lesion. Our aim is to make clinicians aware of bisphosphonate associated osteonecrosis of the jaw to prevent misdiagnosis and initiate proper treatment at the earliest. We present the case of a breast cancer patient with multiple bony metastases and a jaw lesion presumed to be metastases. After no response to palliative radiation, repeat radiological imaging studies revealed osteonecrosis of the jaw. Correlating a patient's clinical information with findings on diagnostic imaging studies, such as SPECT bone and CT scans, can help identify this potential complication of bisphosphonate treatment. Early diagnosis helps minimize unnecessary biopsies and allows for the proper treatment to be instituted.
颌骨坏死通常是双膦酸盐治疗的一种潜在并发症。在癌症患者中，这种疾病实体可能被误诊为转移灶。我们的目的是让临床医生了解双膦酸盐相关的颌骨坏死，以防止误诊并尽早开始适当的治疗。我们报告一例乳腺癌患者，有多处骨转移，颌部病变被推测为转移灶。在姑息性放疗无反应后，重复的放射影像学研究显示为颌骨坏死。将患者的临床信息与诊断性影像学研究结果（如SPECT骨扫描和CT扫描）相关联，有助于识别这种双膦酸盐治疗的潜在并发症。早期诊断有助于减少不必要的活检，并能进行适当的治疗。
