Abou Al-Shaar Hussam, Qutob Safi, Abu-Zaid Ahmed, Azzam Ayman, Amin Tarek, Mohammed Shamayel
College of Medicine, Alfaisal University, P.O. Box 50927, Riyadh 11533, Saudi Arabia.
Oncology Center, King Faisal Specialist Hospital and Research Center, P.O. Box 3354, Riyadh 11211, Saudi Arabia.
Case Rep Oncol Med. 2014;2014:296961. doi: 10.1155/2014/296961. Epub 2014 Mar 4.
Pleural schwannomas are exceedingly rare neoplasms of the thoracic cavity. To the best of our knowledge, less than 20 cases have been reported in the medical English literature. Herein, we report the case of primary pleural benign myxoid schwannoma in an 18-year-old female. The patient was originally referred to our tertiary care hospital for further management of right adrenal gland mass. Physical examination and all laboratory tests were normal. Contrast-enhanced computed tomography scan showed a 4.2 × 3.2 cm, heterogeneous noncalcified mass involving the right adrenal gland region. The right renal vein and inferior vena cava were intact. There was no pleural effusion, ascites, or lymphadenopathy. No pelvic masses were identified. Patient was scheduled for surgical resection. On laparotomy, the mass was not found in its radiologically expected location, and the right kidney and right adrenal gland were intact. The right-sided lower part of diaphragm was opened, and the mass was interestingly found inside the thorax attached to the pleura, and resected successfully. A final histopathological diagnosis of primary pleural benign myxoid schwannoma was established. At a postoperative 6-month followup, there was no radiological evidence of tumor recurrence. Furthermore, literature review on pleural schwannomas is also presented.
胸膜神经鞘瘤是胸腔极为罕见的肿瘤。据我们所知,医学英文文献中报道的病例不到20例。在此,我们报告一例18岁女性原发性胸膜良性黏液样神经鞘瘤的病例。该患者最初因右肾上腺肿块被转诊至我们的三级医疗中心进一步治疗。体格检查和所有实验室检查均正常。增强计算机断层扫描显示右肾上腺区域有一个4.2×3.2厘米、不均匀的非钙化肿块。右肾静脉和下腔静脉完整。无胸腔积液、腹水或淋巴结病。未发现盆腔肿块。患者计划接受手术切除。剖腹手术时,在放射学预期位置未发现肿块,右肾和右肾上腺完整。打开右侧膈肌下部,有趣的是在胸腔内发现肿块附着于胸膜,并成功切除。最终确立了原发性胸膜良性黏液样神经鞘瘤的组织病理学诊断。术后6个月随访时,影像学检查未发现肿瘤复发迹象。此外,还对胸膜神经鞘瘤的文献进行了综述。