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根据实体瘤疗效评价标准,容积测量过程在肿瘤学成像试验中对肿瘤筛查和评估的重要性。

Importance of volumetric measurement processes in oncology imaging trials for screening and evaluation of tumors as per response evaluation criteria in solid tumors.

作者信息

Vemuri Ravi Chandra, Jarecha Rudresh, Hwi Kim Kah, Gundamaraju Rohit, Maruthikanth Aripaka, Kulkarni Aravindrao, Reddy Sundeep

机构信息

Department of Medical Imaging, Core Imaging Laboratory, Parexel International, Hyderabad, AP, India E-mail : :

出版信息

Asian Pac J Cancer Prev. 2014;15(5):2375-8. doi: 10.7314/apjcp.2014.15.5.2375.

DOI:10.7314/apjcp.2014.15.5.2375
PMID:24716987
Abstract

Cancer, like any disease, is a pathologic biological process. Drugs are designed to interfere with the pathologic process and should therefore also be validated using a functional screening method directed at these processes. Screening for cancers at an appropriate time and also evaluating results is also very important. Volumetric measurement helps in better screening and evaluation of tumors. Volumetry is a process of quantification of the tumors by identification (pre-cancerous or target lesion) and measurement. Volumetric image analysis allows an accurate, precise, sensitive, and medically valuable assessment of tumor response. It also helps in identifying possible outcomes such disease progression (PD) or complete response as per Response Evaluation Criteria in Solid Tumors (RECIST).

摘要

癌症与任何疾病一样,是一种病理生物学过程。药物旨在干扰病理过程,因此也应使用针对这些过程的功能筛选方法进行验证。在适当的时候筛查癌症并评估结果也非常重要。体积测量有助于更好地筛查和评估肿瘤。体积测定是通过识别(癌前或靶病变)和测量对肿瘤进行定量的过程。体积图像分析能够对肿瘤反应进行准确、精确、灵敏且具有医学价值的评估。它还有助于根据实体瘤疗效评价标准(RECIST)识别诸如疾病进展(PD)或完全缓解等可能的结果。

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