Maĭborodin I V, Minikeev I M, Kim S A, Ragimova T M
Stomatologiia (Mosk). 2014;93(1):72-9.
The analysis of the scientific literature devoted to organ and tissue changes of oral cavity at the chronic renal insufficiency (CRI)is made. The number of patients in an end-stage of CRI constantly increases and patients receiving renal replacement therapy including hemodialysis, peritoneal dialysis or renal transplantation will comprise an enlarging segment of the dental patient population. Owing to CRI and its treatment there is a set of changes of teeth and oral cavity fabrics which remain even in a end-stage. Renal replacement therapy can affect periodontal tissues including gingival hyperplasia in immune suppressed renal transplantation patients and increased levels of bacterial contamination, gingival inflammation, formation of calculus, and possible increased prevalence and severity of destructive periodontal diseases. Besides, the presence of undiagnosed periodontitis may have significant effects on the medical management of the patients in end-stage of CRI.
对有关慢性肾功能不全（CRI）时口腔器官和组织变化的科学文献进行了分析。CRI终末期患者的数量持续增加，接受包括血液透析、腹膜透析或肾移植在内的肾脏替代治疗的患者将在牙科患者群体中占越来越大的比例。由于CRI及其治疗，牙齿和口腔组织会出现一系列变化，这些变化甚至在终末期依然存在。肾脏替代治疗可影响牙周组织，包括免疫抑制的肾移植患者出现牙龈增生、细菌污染水平升高、牙龈炎症、牙石形成，以及破坏性牙周疾病的患病率和严重程度可能增加。此外，未诊断出的牙周炎可能对CRI终末期患者的医疗管理产生重大影响。
