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胰腺实性假乳头状瘤:诊断、治疗及预后

Solid pseudopapillary tumour of the pancreas: diagnosis, treatment, and prognosis.

作者信息

Cecka F, Jon B, Subrt Z, Ferko A

出版信息

Acta Chir Belg. 2014 Jan-Feb;114(1):58-62.

PMID:24720140
Abstract

BACKGROUND

Solid pseudopapillary tumour (SPT) of the pancreas is a relatively rare entity which most commonly occurs in young women. In this paper we report our clinical experience together with the current knowledge on the diagnostics, treatment and prognosis of this rare tumour.

METHODS

We reviewed hospital records of patients diagnosed with a solid pseudopapillary tumour of the pancreas between January 2002 and December 2011 at the Department of Surgery, University Hospital Hradec Králové, Czech Republic. Clinical, operative, pathological data were obtained on all the patients.

RESULTS

Over the 10-year period of the study we performed 181 planned pancreatic resections in our department. Overall, the 30-day postoperative mortality rate in this series of patients was 2.2%. SPT was diagnosed in 4 cases. All the patients were women and the average age was 34 years. Preoperative endosonography with biopsy sample was performed in all the patients and the diagnosis of SPT was known in all the patients before the surgical procedure.

CONCLUSIONS

The current knowledge of SPT is based only on case reports and small series. It typically occurs in young women and therefore the presence of a large pancreatic mass in a young woman may suggest a diagnosis of SPT. SPT has a low malignant potential and the prognosis is excellent following complete surgical resection in the majority of the cases.

摘要

背景

胰腺实性假乳头状瘤(SPT)是一种相对罕见的疾病,最常见于年轻女性。在本文中,我们报告了我们的临床经验以及关于这种罕见肿瘤的诊断、治疗和预后的当前知识。

方法

我们回顾了2002年1月至2011年12月期间在捷克共和国赫拉德茨克拉洛韦大学医院外科被诊断为胰腺实性假乳头状瘤的患者的医院记录。获取了所有患者的临床、手术和病理数据。

结果

在这项研究的10年期间,我们科室共进行了181例计划性胰腺切除术。总体而言,该系列患者的术后30天死亡率为2.2%。有4例被诊断为SPT。所有患者均为女性,平均年龄为34岁。所有患者均进行了术前超声内镜检查并取活检样本,所有患者在手术前均已知SPT的诊断。

结论

目前关于SPT的知识仅基于病例报告和小系列研究。它通常发生在年轻女性中,因此年轻女性出现较大的胰腺肿块可能提示SPT的诊断。SPT的恶性潜能较低,大多数病例在完整手术切除后预后良好。

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