Tyler Wakenda, Bukata Susan, O'Keefe Regis
Department of Orthopaedic Surgery, University of Rochester, 601 Elmwood Avenue, Box 665, Rochester, NY 14642, USA.
Department of Orthopaedic Surgery, University of California, Los Angeles, Los Angeles, California, USA.
Clin Geriatr Med. 2014 May;30(2):349-59. doi: 10.1016/j.cger.2014.01.010. Epub 2014 Mar 4.
Atypical femur fractures were first reported in 2007 and are now recognized as a unique clinical entity. They occur along the shaft of the femur extending from the subtrochanteric region proximally to the distal femoral metaphysis. These fractures have an increased incidence in patients taking bisphosphonates for osteoporosis and develop as stress reactions in the lateral cortex of the femoral shaft. The fractures often have a distinct radiographic appearance with thickening or beaking of the lateral cortex. Treatment should be initiated immediately. There is a higher incidence of complications with atypical fractures. Early detection of these fractures can greatly reduce morbidity.
非典型股骨骨折于2007年首次被报道，如今被视为一种独特的临床实体。它们发生在股骨干，从近端的转子下区域延伸至远端股骨干骺端。这些骨折在服用双膦酸盐治疗骨质疏松症的患者中发病率增加，是股骨干外侧皮质的应力反应所致。骨折通常具有独特的影像学表现，外侧皮质增厚或呈喙状。应立即开始治疗。非典型骨折的并发症发生率较高。早期发现这些骨折可大大降低发病率。
