Onyilagha J C, Omenyi S N, Snyder R S
Department of Applied Biology, Anambra State University of Technology, Enugu, Nigeria.
Cell Biophys. 1989 Jun;14(3):217-30. doi: 10.1007/BF02797269.
The applicability of some existing droplet sedimentation theories to erythrocyte suspensions was investigated using glutaraldehyde-fixed erythrocytes from horse, canine, pig, chicken, and human. The Svensson criteria were shown to underestimate the load supportable by a density gradient. The available theories on droplet formation times could not predict each other, and the data on erythrocyte suspensions, especially at high suspension concentrations. It was finally argued that, since the behavior of erythrocytes was not controlled by the diffusion process, the erythrocyte suspensions were not expected to exhibit lasting or absolute stability even when the particle load was small.
利用来自马、犬、猪、鸡和人类的戊二醛固定红细胞,研究了一些现有液滴沉降理论对红细胞悬液的适用性。结果表明,斯文森标准低估了密度梯度可承受的负荷。关于液滴形成时间的现有理论相互之间无法预测,也无法预测红细胞悬液的数据,尤其是在高悬浮浓度下的数据。最后有人认为,由于红细胞的行为不受扩散过程控制,即使颗粒负荷较小,红细胞悬液也不会表现出持久或绝对的稳定性。