Webb M J
Baillieres Clin Obstet Gynaecol. 1989 Mar;3(1):83-94. doi: 10.1016/s0950-3552(89)80044-6.
A series of 210 consecutive operations for ovarian cancer performed by the author over a five-year period were analysed in order to assess the ability to perform adequate cytoreduction. Over 63% of the patients had Stage III or IV disease. Bowel resection was necessary in 50 cases, and the surgery was generally well tolerated. Debulking was assessed as a percentage of tumour volume reduction and also by the size of residual tumour after operation. Over 90% tumour volume reduction was accomplished in 82.7% of all cases (75% of Stage III cases), and optimal cytoreduction of nodules to less than or equal to 1.5 cm was achieved in 70.8% of cases (60% of Stage III cases). Survival analysis confirmed the importance of cytoreduction in the management of this disease.
作者在五年期间连续进行了210例卵巢癌手术，对这些手术进行分析以评估实施充分肿瘤细胞减灭术的能力。超过63%的患者患有III期或IV期疾病。50例患者需要进行肠切除术，手术总体耐受性良好。肿瘤细胞减灭程度通过肿瘤体积缩小的百分比以及术后残余肿瘤的大小来评估。在所有病例的82.7%（III期病例的75%）中实现了超过90%的肿瘤体积缩小，在70.8%的病例（III期病例的60%）中实现了将结节最佳细胞减灭至小于或等于1.5厘米。生存分析证实了肿瘤细胞减灭术在该疾病治疗中的重要性。
