Hudson C N, Potsides P, Curling O M
Department of Obstetrics & Gynaecology, St Bartholomew's Hospital, London.
J R Soc Med. 1991 Apr;84(4):206-9. doi: 10.1177/014107689108400408.
The varied application of surgery to the initial treatment of 908 cases of primary ovarian cancer is analysed. In patients with advanced disease (FIGO Stages IIb, III and IV) 256 (46%) of 555 women achieved minimal residual disease status by primary surgery and this proportion fell to 24% when only stages III and IV were considered; of these cases 7% underwent adjunctive intestinal resection or urinary tract surgery. Although not in a clinical trial situation the women achieving minimal residual disease status before chemotherapy survived better in the short term, although long-term survival remained disappointing. In early disease 3% of young women have been subjected to hysterectomy and removal of both ovaries. By contrast, in 16% of women over the age of 40 years with early ovarian cancer bilateral oophorectomy was not carried out.
分析了手术在908例原发性卵巢癌初始治疗中的不同应用情况。在晚期疾病（国际妇产科联盟（FIGO）分期IIb、III和IV期）患者中，555名女性中有256名（46%）通过初次手术达到了最小残留病灶状态；仅考虑III期和IV期时，这一比例降至24%；在这些病例中，7%接受了辅助性肠切除术或泌尿道手术。尽管并非处于临床试验情况，但在化疗前达到最小残留病灶状态的女性短期内生存情况较好，不过长期生存情况仍令人失望。在早期疾病中，3%的年轻女性接受了子宫切除术和双侧卵巢切除术。相比之下，在40岁以上患有早期卵巢癌的女性中，16%未进行双侧卵巢切除术。
