Raju T N K, Mercer B M, Burchfield D J, Joseph G F
The Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA.
The Society for Maternal-Fetal Medicine and Case Western Reserve University-MetroHealth Medical Center, Cleveland, OH, USA.
J Perinatol. 2014 May;34(5):333-42. doi: 10.1038/jp.2014.70. Epub 2014 Apr 10.
This is an executive summary of a workshop on the management and counseling issues of women anticipated to deliver at a periviable gestation (broadly defined as 20 0/7 through 25 6/7 weeks of gestation), and the treatment options for the newborn. Upon review of the available literature, the workshop panel noted that the rates of neonatal survival and neurodevelopmental disabilities among the survivors vary greatly across the periviable gestations and are significantly influenced by the obstetric and neonatal management practices (for example, antenatal steroid, tocolytic agents and antibiotic administration; cesarean birth; and local protocols for perinatal care, neonatal resuscitation and intensive care support). These are, in turn, influenced by the variations in local and regional definitions of limits of viability. Because of the complexities in making difficult management decisions, obstetric and neonatal teams should confer prior to meeting with the family, when feasible. Family counseling should be coordinated with the goal of creating mutual trust, respect and understanding, and should incorporate evidence-based counseling methods. Since clinical circumstances can change rapidly with increasing gestational age, counseling should include discussion of the benefits and risks of various maternal and neonatal interventions at the time of counseling. There should be a plan for follow-up counseling as clinical circumstances evolve. The panel proposed a research agenda and recommended developing educational curricula on the care and counseling of families facing the birth of a periviable infant.
这是关于预计在可存活孕周(广义定义为妊娠20 0/7至25 6/7周)分娩的女性的管理与咨询问题以及新生儿治疗方案研讨会的执行摘要。在查阅现有文献后,研讨会小组指出,在整个可存活孕周范围内,新生儿存活率和存活者神经发育障碍发生率差异很大,并且受到产科和新生儿管理实践(例如,产前使用类固醇、宫缩抑制剂和抗生素;剖宫产;以及围产期护理、新生儿复苏和重症监护支持的当地方案)的显著影响。这些反过来又受到当地和地区对存活极限定义差异的影响。由于做出困难管理决策存在复杂性,产科和新生儿团队应在可行时,在与家属会面之前进行协商。应协调家属咨询工作,目标是建立相互信任、尊重和理解,并应采用循证咨询方法。由于临床情况会随着孕周增加而迅速变化,咨询应包括在咨询时讨论各种孕产妇和新生儿干预措施的益处和风险。随着临床情况的发展,应有后续咨询计划。该小组提出了一项研究议程,并建议制定关于为面临可存活孕周婴儿出生的家庭提供护理和咨询的教育课程。