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近可存活儿分娩:尤妮斯·肯尼迪·施莱佛国家儿童健康与人类发展研究所、母胎医学协会、美国儿科学会及美国妇产科医师学会联合研讨会执行摘要

Periviable birth: executive summary of a Joint Workshop by the Eunice Kennedy Shriver National Institute of Child Health and Human Development, Society for Maternal-Fetal Medicine, American Academy of Pediatrics, and American College of Obstetricians and Gynecologists.

作者信息

Raju T N K, Mercer B M, Burchfield D J, Joseph G F

机构信息

The Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA.

The Society for Maternal-Fetal Medicine and Case Western Reserve University-MetroHealth Medical Center, Cleveland, OH, USA.

出版信息

J Perinatol. 2014 May;34(5):333-42. doi: 10.1038/jp.2014.70. Epub 2014 Apr 10.

DOI:10.1038/jp.2014.70
PMID:24722647
Abstract

This is an executive summary of a workshop on the management and counseling issues of women anticipated to deliver at a periviable gestation (broadly defined as 20 0/7 through 25 6/7 weeks of gestation), and the treatment options for the newborn. Upon review of the available literature, the workshop panel noted that the rates of neonatal survival and neurodevelopmental disabilities among the survivors vary greatly across the periviable gestations and are significantly influenced by the obstetric and neonatal management practices (for example, antenatal steroid, tocolytic agents and antibiotic administration; cesarean birth; and local protocols for perinatal care, neonatal resuscitation and intensive care support). These are, in turn, influenced by the variations in local and regional definitions of limits of viability. Because of the complexities in making difficult management decisions, obstetric and neonatal teams should confer prior to meeting with the family, when feasible. Family counseling should be coordinated with the goal of creating mutual trust, respect and understanding, and should incorporate evidence-based counseling methods. Since clinical circumstances can change rapidly with increasing gestational age, counseling should include discussion of the benefits and risks of various maternal and neonatal interventions at the time of counseling. There should be a plan for follow-up counseling as clinical circumstances evolve. The panel proposed a research agenda and recommended developing educational curricula on the care and counseling of families facing the birth of a periviable infant.

摘要

这是关于预计在可存活孕周(广义定义为妊娠20 0/7至25 6/7周)分娩的女性的管理与咨询问题以及新生儿治疗方案研讨会的执行摘要。在查阅现有文献后,研讨会小组指出,在整个可存活孕周范围内,新生儿存活率和存活者神经发育障碍发生率差异很大,并且受到产科和新生儿管理实践(例如,产前使用类固醇、宫缩抑制剂和抗生素;剖宫产;以及围产期护理、新生儿复苏和重症监护支持的当地方案)的显著影响。这些反过来又受到当地和地区对存活极限定义差异的影响。由于做出困难管理决策存在复杂性,产科和新生儿团队应在可行时,在与家属会面之前进行协商。应协调家属咨询工作,目标是建立相互信任、尊重和理解,并应采用循证咨询方法。由于临床情况会随着孕周增加而迅速变化,咨询应包括在咨询时讨论各种孕产妇和新生儿干预措施的益处和风险。随着临床情况的发展,应有后续咨询计划。该小组提出了一项研究议程,并建议制定关于为面临可存活孕周婴儿出生的家庭提供护理和咨询的教育课程。

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Neurodevelopmental outcomes at 4 to 8 years of children born at 22 to 25 weeks' gestational age: a meta-analysis.22 至 25 孕周出生的儿童在 4 至 8 岁时的神经发育结局:一项荟萃分析。
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Neurodevelopmental outcome of extremely premature infants exposed to incomplete, no or complete antenatal steroids.
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In-utero transfer, survival-focused care and survival to 28-days at 22-24 weeks' gestation pre- and post- implementation of an extreme prematurity management guideline in Victoria, Australia.在澳大利亚维多利亚州实施极早产儿管理指南前后,22-24 孕周的宫内转移、以生存为中心的护理和生存至 28 天的情况。
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Positioning comfort measures in antenatal counselling for periviable infants.为接近可存活孕周的胎儿进行产前咨询时的体位舒适措施
Sociol Health Illn. 2025 Feb;47(2):e13852. doi: 10.1111/1467-9566.13852. Epub 2024 Oct 10.
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The Ethics and Practice of Periviability Care.围生期可存活护理的伦理与实践
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