Hawkes Anna L, Pakenham Kenneth I, Chambers Suzanne K, Patrao Tania A, Courneya Kerry S
School of Public Health and Social Work, Queensland University of Technology, Victoria Park Road, Kelvin Grove, Brisbane, Queensland, 4059, Australia,
Ann Behav Med. 2014 Dec;48(3):359-70. doi: 10.1007/s12160-014-9610-2.
Multiple health behavior change can ameliorate adverse effects of cancer.
The purpose of this study was to determine the effects of a multiple health behavior change intervention (CanChange) for colorectal cancer survivors on psychosocial outcomes and quality of life.
A total of 410 colorectal cancer survivors were randomized to a 6-month telephone-based health coaching intervention (11 sessions using acceptance and commitment therapy strategies focusing on physical activity, weight management, diet, alcohol, and smoking) or usual care. Posttraumatic growth, spirituality, acceptance, mindfulness, distress, and quality of life were assessed at baseline, 6 and 12 months.
Significant intervention effects were observed for posttraumatic growth at 6 (7.5, p < 0.001) and 12 months (4.1, p = 0.033), spirituality at 6 months (1.8, p = 0.011), acceptance at 6 months (0.2, p = 0.005), and quality of life at 6 (0.8, p = 0.049) and 12 months (0.9, p = 0.037).
The intervention improved psychosocial outcomes and quality of life (physical well-being) at 6 months with most effects still present at 12 months. (
ACTRN12608000399392).
多种健康行为改变可改善癌症的不良影响。
本研究旨在确定针对结直肠癌幸存者的多种健康行为改变干预措施（CanChange）对心理社会结局和生活质量的影响。
总共410名结直肠癌幸存者被随机分为接受为期6个月的电话健康指导干预（11次课程，采用接受与承诺疗法策略，重点关注身体活动、体重管理、饮食、饮酒和吸烟）或常规护理。在基线、6个月和12个月时评估创伤后成长、精神性、接纳、正念、痛苦和生活质量。
在6个月时（7.5，p < 0.001）和12个月时（4.1，p = 0.033）观察到创伤后成长有显著干预效果，6个月时精神性（1.8，p = 0.011）、接纳（0.2，p = 0.005）有显著干预效果，6个月时（0.8，p = 0.049）和12个月时（0.9，p = 0.037）生活质量有显著干预效果。
该干预在6个月时改善了心理社会结局和生活质量（身体健康），且大部分效果在12个月时仍然存在。（试验注册号：ACTRN12608000399392）
