Lynch Brigid M, Courneya Kerry S, Sethi Parneet, Patrao Tania A, Hawkes Anna L
Physical Activity Laboratory, Baker IDI Heart and Diabetes Institute, Melbourne, Victoria, Australia; Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia.
Cancer. 2014 Sep 1;120(17):2665-72. doi: 10.1002/cncr.28773. Epub 2014 May 9.
Sedentary behavior may independently contribute to morbidity and mortality among survivors of colorectal cancer. In the current study, the authors assessed whether a telephone-delivered multiple health behavior change intervention had an effect on the sedentary behavior of recently diagnosed colorectal cancer survivors.
A total of 410 participants were recruited through the Queensland Cancer Registry and randomized to the health coaching (intervention) or usual-care (control) group. Eleven health coaching sessions addressing multiple health behaviors, including sedentary behavior, were delivered over a period of 6 months. Data were collected at baseline (before randomization), at 6 months, and at 12 months via a telephone interview.
At 12 months, there was a significant decrease noted in the hours per day of sedentary time in both the health coaching (-1.21; 95% confidence interval [95% CI], -1.71 to -0.70) and usual-care groups (-0.55; 95% CI, -1.06 to -0.05), but the between-group difference was not found to be statistically significant (-0.65; 95% CI, -1.37 to 0.06 [P = .07]). In stratified subgroup analyses, the multiple health behavior change intervention was found to have a significant effect on total sedentary time (hours/day) at 12 months in survivors of colorectal cancer who were aged > 60 years (-0.90; 95% CI, -1.80 to -0.01 [P = .05]), male (-1.33; 95% CI, -2.44 to -0.21 [P = .02]), and nonobese (-1.10; 95% CI, -1.96 to -0.25; [P = .01]).
Incorporating simple messages about limiting sedentary behaviors into a multiple health behavior change intervention was found to have modest effects on sedentary behavior. A sedentary behavior-specific intervention strategy may be required to achieve substantial changes in sedentary behavior among colorectal cancer survivors.
久坐行为可能独立导致结直肠癌幸存者发病和死亡。在本研究中，作者评估了通过电话提供的多种健康行为改变干预措施对近期诊断出的结直肠癌幸存者的久坐行为是否有影响。
通过昆士兰癌症登记处招募了410名参与者，并将其随机分为健康指导（干预）组或常规护理（对照）组。在6个月的时间里进行了11次针对多种健康行为（包括久坐行为）的健康指导课程。通过电话访谈在基线（随机分组前）、6个月和12个月时收集数据。
在12个月时，健康指导组（-1.21；95%置信区间[95%CI]，-1.71至-0.70）和常规护理组（-0.55；95%CI，-1.06至-0.05）的每日久坐时间均显著减少，但组间差异无统计学意义（-0.65；95%CI，-1.37至0.06[P = 0.07]）。在分层亚组分析中，发现多种健康行为改变干预措施对年龄>60岁（-0.9；95%CI，-1.80至-0.01[P = 0.05]）、男性（-1.33；95%CI，-2.44至-0.21[P = 0.02]）和非肥胖（-1.10；95%CI，-1.96至-0.25；[P = 0.01]）的结直肠癌幸存者在12个月时的总久坐时间（小时/天）有显著影响。
将关于限制久坐行为的简单信息纳入多种健康行为改变干预措施中，发现对久坐行为有适度影响。可能需要一种针对久坐行为的干预策略，以在结直肠癌幸存者中实现久坐行为的实质性改变。
