尤因肉瘤患者骨骼中钙、氯、镁、钠和磷的质量分数。

The Ca, Cl, Mg, Na, and P mass fractions in human bone affected by Ewing's sarcoma.

作者信息

Zaichick Vladimir, Zaichick Sofia

机构信息

Radionuclide Diagnostics Department, Medical Radiological Research Centre, Koroleva St. 4, Obninsk, 249036, Kaluga Region, Russia,

出版信息

Biol Trace Elem Res. 2014 Jun;159(1-3):32-8. doi: 10.1007/s12011-014-9966-y. Epub 2014 Apr 11.

DOI:10.1007/s12011-014-9966-y

PMID:24723217

Abstract

The Ca, Cl, Mg, Na, and P contents and Ca/P, Ca/Mg, Ca/Na, Cl/Ca, and Cl/Na ratios in samples of intact bone, inflamed bone, and Ewing's sarcoma tissue were investigated by neutron activation analysis with high-resolution spectrometry of short-lived radionuclides. In Ewing's sarcoma tissue, the mass fractions of Cl and Na are higher and the mass fractions of Ca and Mg are lower than those of both normal and inflamed bone tissues. It was shown that the levels of Ca and Cl mass fractions and also levels of the Ca/Cl and Cl/Na ratios can be used as an additional test for differential diagnosis between inflamed (or normal) bone and Ewing's sarcoma.

摘要

采用短寿命放射性核素高分辨率光谱中子活化分析法，对完整骨、炎症骨和尤因肉瘤组织样本中的钙、氯、镁、钠和磷含量以及钙/磷、钙/镁、钙/钠、氯/钙和氯/钠比值进行了研究。在尤因肉瘤组织中，氯和钠的质量分数高于正常和炎症骨组织，而钙和镁的质量分数低于正常和炎症骨组织。结果表明，钙和氯的质量分数水平以及钙/氯和氯/钠比值水平可作为炎症（或正常）骨与尤因肉瘤鉴别诊断的附加检测指标。