Mellin K B, Kondler R
Fortschr Ophthalmol. 1989;86(2):129-31.
A randomized prospective study was done to analyze conjunctival wound closure after extracapsular cataract extraction in 100 patients. When the conjunctival wound was closed with stitches 36.7% of the patients reported the sensation of a foreign body in the eye; the same sensation was reported by 7.8% after fibrin sealant. On postoperative day 7, 11.8% of the patients had conjunctival wound dehiscence after the wound had been adapted with fibrin sealant and in 32.6% after using stitches to close the conjunctival wound. Using a fibrin sealant for conjunctival wound closure significantly reduces the postoperative foreign body sensation and wound dehiscence of the conjunctiva. The main problem with fibrin sealant was handling the glue during the operation.
进行了一项随机前瞻性研究，以分析100例患者在白内障囊外摘除术后结膜伤口的闭合情况。当用缝线闭合结膜伤口时，36.7%的患者报告有眼部异物感；使用纤维蛋白密封剂后，有7.8%的患者报告有相同的感觉。术后第7天，在使用纤维蛋白密封剂调整伤口后，11.8%的患者出现结膜伤口裂开，而在使用缝线闭合结膜伤口后，这一比例为32.6%。使用纤维蛋白密封剂闭合结膜伤口可显著降低术后异物感和结膜伤口裂开的发生率。纤维蛋白密封剂的主要问题是手术过程中胶水的操作。
