Iaitskiĭ N A, Gelazoniia R V, Khatelishvili V M
Khirurgiia (Mosk). 1989 May(5):51-4.
The authors analyse the results of surgical treatment and the findings of morphological studies in 181 patients with cancer of the colon. Extended radical operative interventions were conducted in spreading of the tumor to adjacent organs and tissues in 95 (67.5%) of 140 patients. Postoperative mortality was 12.6%. Growth of the tumor into the adjacent anatomical structures was confirmed in 64.5% of cases. The prognosis of the disease was found to be determined to a greater measure by the histological structure of the tumor and metastasis to the regional lymph nodes rather than by localized spread of the tumor in patients treated by radical operation. Amendments to the formulations of stages III and IV of the clinical classification of cancer of the colon are suggested.
作者分析了181例结肠癌患者的手术治疗结果和形态学研究结果。140例患者中有95例(67.5%)因肿瘤扩散至相邻器官和组织而进行了扩大根治性手术干预。术后死亡率为12.6%。64.5%的病例证实肿瘤已侵入相邻解剖结构。结果发现,对于接受根治性手术治疗的患者,疾病的预后在更大程度上取决于肿瘤的组织结构和区域淋巴结转移情况,而非肿瘤的局部扩散情况。建议对结肠癌临床分类的III期和IV期的表述进行修订。