Çimen Dilay, Bulcun Emel, Ekici Aydanur, Güngör Ömür, Ekici Mehmet
Faculty of Medicine, Department of Pulmonary Medicine, University of Kirikkale, Kirikkale, Turkey.
Clin Respir J. 2015 Oct;9(4):512-5. doi: 10.1111/crj.12137. Epub 2014 May 15.
Round pneumonia (RP) is a rare radiological presentation of a subtype of lobar pneumonia that arises because of a developmental defect in connective tissues (pores of Köhn and channels of Lambert). The round appearance on chest X-ray (CXR) is thought to occur from an infectious process that spreads from small peripheral alveoli centrifugally through interalveolar channels via the pores of Kohn and the canals of Lambert. This explains the nonsegmental distribution and shape of RP. The pathogenesis of RP is unknown. An alternative theory holds that RP in children occurs because of underdeveloped pores of Kohn and the absence of canals of Lambert, limiting the spread of the organism and resulting in a focal, round mass seen on radiographs. As a result of this developmental defect, dissemination of infection remains in a limited area. While this is a well-known entity in childhood, it has been described infrequently in adults. Lesions of RP are not necessarily round; oval lesions can also be seen. It is a radiological subtype of the pneumonia subtype and presents as a solitary nodule or a mass lesion in CXR.
We presented two cases of RP. One mimicked and was mistaken for pulmonary infarction because of triangular pleural-based density and the other mimicked pulmonary malignancy because of a homogeneous triangular opacity based on the pleura on the posteroanterior radiography and computed tomography.
These cases were presented because of RP's importance, and RP should be considered a part of differential diagnosis of pulmonary infarct and lung tumor.
圆形肺炎(RP)是大叶性肺炎一种亚型的罕见影像学表现,其产生是由于结缔组织(科恩孔和兰伯特通道)发育缺陷所致。胸部X线(CXR)上的圆形表现被认为是由感染过程引起的,该感染过程从小的外周肺泡通过科恩孔和兰伯特通道沿肺泡间通道离心扩散。这解释了RP的非节段性分布和形态。RP的发病机制尚不清楚。另一种理论认为,儿童发生RP是因为科恩孔发育不全且缺乏兰伯特通道,限制了病原体的扩散,导致在X线片上出现局灶性圆形肿块。由于这种发育缺陷,感染传播局限于有限区域。虽然这在儿童中是一种已知的疾病,但在成人中鲜有报道。RP的病灶不一定是圆形的;椭圆形病灶也可见到。它是肺炎亚型的一种影像学类型,在CXR上表现为孤立性结节或肿块样病变。
我们报告了2例RP病例。1例因三角形胸膜下密度影而被误诊为肺梗死,另一例因正位胸片和计算机断层扫描显示胸膜下均匀三角形致密影而被误诊为肺恶性肿瘤。
之所以报告这些病例是因为RP的重要性,RP应被视为肺梗死和肺肿瘤鉴别诊断的一部分。