School of the Built Environment, Heriot-Watt University, UK.
Public Health. 2014 Apr;128(4):376-9. doi: 10.1016/j.puhe.2014.01.004. Epub 2014 Apr 13.
Understanding of the social determinants of cancer in adults and the very old is still limited. The aim of this study was to provide recent evidence on the social correlates of adult total cancer in a national and population-based setting.
A cross-sectional study in the recent years between 2009 and 2010.
Data was retrieved and analysed from the UK Longitudinal Household Survey. Information on demographics, living and work conditions, self-reported cancer and age of onset was obtained by household interview. Analyses included Chi-squared test, t-test, and multilevel logistic regression modelling.
Of 50,994 people included in the cohort, 1623 (3.5%) had ever cancer. Of these, 1592 (98.0%) occurred in adulthood (16y+) and only 109 people had their first cancer (incident cancer) at the age when they were interviewed. In the middle-aged and young adults, being female (OR 1.57, 95%CI 1.20-2.06, P = 0.001 and OR 2.04, 95%CI 1.07-3.87, P = 0.03, respectively), not born in the UK (OR 0.54, 95%CI 0.34-0.88, P = 0.01 and OR 0.31, 95%CI 0.09-1.02, P = 0.05, respectively), and being obese/overweight (OR 1.49, 95%CI 1.07-2.07, P = 0.02 and OR 2.34, 95%CI 1.17-4.66, P = 0.02, respectively) were associated with total cancer. However, no associated social factors of cancer in the very old were found. Moreover, prevalence was higher in East Midlands (OR 1.73, 95%CI 1.00-3.00, P = 0.05) but not other regions, compared to London region.
Social environment seems to continue playing a role in the aetiology of cancer in adults, although novel and/or pooled investigation for the very old would be warranted.
成人和高龄人群癌症的社会决定因素仍知之甚少。本研究旨在为全国范围内成人总体癌症的社会相关性提供最新证据。
2009 年至 2010 年期间的一项横断面研究。
从英国纵向家庭调查中获取和分析数据。通过家庭访谈获得人口统计学、生活和工作条件、自我报告的癌症和发病年龄信息。分析包括卡方检验、t 检验和多水平逻辑回归模型。
在纳入的 50994 名队列人群中，有 1623 人（3.5%）患有癌症。其中，1592 人（98.0%）发生在成年期（16 岁及以上），仅有 109 人在接受访谈时首次患有癌症（新发癌症）。在中年和青年人群中，女性（OR 1.57，95%CI 1.20-2.06，P=0.001 和 OR 2.04，95%CI 1.07-3.87，P=0.03）、非英国出生（OR 0.54，95%CI 0.34-0.88，P=0.01 和 OR 0.31，95%CI 0.09-1.02，P=0.05）和肥胖/超重（OR 1.49，95%CI 1.07-2.07，P=0.02 和 OR 2.34，95%CI 1.17-4.66，P=0.02）与总癌症相关。然而，在高龄人群中未发现与癌症相关的社会因素。此外，与伦敦地区相比，东米德兰兹地区（OR 1.73，95%CI 1.00-3.00，P=0.05）的癌症患病率更高。
社会环境似乎继续在成人癌症的病因学中发挥作用，尽管需要对高龄人群进行新的或综合的调查。
