Lupski J R, Godson G N
Bioessays. 1989 May;10(5):152-7. doi: 10.1002/bies.950100504.
In Escherichia coli, the workhorse of molecular biology, a single operon is involved in the replication, transcription and translation of genetic information. This operon is controlled in a complex manner involving multiple cis-acting regulatory sequences and trans-acting regulatory proteins. It interacts with global regulatory networks by mechanisms which are presently being dissected.
在分子生物学的主力军大肠杆菌中,一个单一的操纵子参与遗传信息的复制、转录和翻译。这个操纵子以一种复杂的方式受到控制,涉及多个顺式作用调节序列和反式作用调节蛋白。它通过目前正在解析的机制与全局调节网络相互作用。