Wen Wu, Sun Guangbin, Sun Bifeng, Liu Chang, Zhang Mingxing
Department of Otorhinolaryngology, Changhai Hospital, Second Military Medical University, Shanghai, 200433, China.
Eur Arch Otorhinolaryngol. 2015 Mar;272(3):517-22. doi: 10.1007/s00405-014-3037-z. Epub 2014 Apr 13.
This study aimed to describe a new titanium thyroplasty implant that can be adjusted with a screw. Six Beagle dogs were randomly divided into experimental and control groups (n = 3). The titanium screw was implanted in the experimental group after the left recurrent laryngeal nerve was cut off under general anaesthesia. This procedure caused arytenoid cartilage internal shift, allowing the vocal cord to locate at the median and the glottis to close during phonation. No other operation was conducted in the control group. Each group, respectively, underwent video laryngoscopy, CT scan and histopathology before and after operation. After 4 months of follow-up, the video laryngoscopy results showed that the left arytenoid cartilage in the experimental group underwent internal adduct and shift, whereas the left vocal cords in the control group located at the paramedian position and exhibited fissure during phonation. CT scan results showed that the adjustable titanium screw was in proper position. Postoperative pathological examination showed that, in addition to early local inflammation, the laryngeal muscle may atrophy. The adjustable titanium screw requires a simple operation and can be significantly adjusted. The effect of the operation can be immediately observed without rejection. Therefore, this method is an efficient treatment for unilateral vocal cord paralysis.
本研究旨在描述一种可通过螺钉进行调节的新型钛质甲状成形术植入物。6只比格犬被随机分为实验组和对照组（n = 3）。实验组在全身麻醉下切断左侧喉返神经后植入钛质螺钉。该操作导致杓状软骨向内移位，使声带在发声时位于正中位且声门闭合。对照组未进行其他手术。每组在手术前后分别接受电子喉镜检查、CT扫描和组织病理学检查。随访4个月后，电子喉镜检查结果显示，实验组左侧杓状软骨向内收并移位，而对照组左侧声带在发声时位于旁正中位且出现裂隙。CT扫描结果显示，可调节钛质螺钉位置合适。术后病理检查显示，除早期局部炎症外，喉肌可能萎缩。可调节钛质螺钉操作简单，可显著调节。手术效果可立即观察到，且无排斥反应。因此，该方法是治疗单侧声带麻痹的有效方法。
