Malay Jhancy, Madhavi N, Satyavani A, Nishanth P, Manikyamba D
Department of Pediatrics, Rangaraya Medical College, Kakinada, Andhra Pradesh, India.
Indian J Pediatr. 2014 Oct;81(10):1099-101. doi: 10.1007/s12098-014-1427-2. Epub 2014 Apr 15.
Intra-pericardial teratoma, most often a benign tumor, is an extremely rare condition in a newborn. It can be a diagnostic and therapeutic challenge if it presents with massive pericardial effusion. Complete surgical excision of the tumor is necessary because of its association with tissues of malignant potential. A 16-d-old newborn was diagnosed with intra pericardial immature teratoma (IT) and managed successfully with multidisciplinary team approach by prompt referral for complete surgical resection followed by adjuvant chemotherapy with carboplatin, etoposide and bleomycin (JEB) to prevent recurrence. The infant is now on close follow up with monitoring of serum alpha fetoprotein (AFP) levels and imaging studies for early diagnosis of recurrence of tumor and chemotherapy related complications.
心包内畸胎瘤大多为良性肿瘤,在新生儿中极为罕见。如果出现大量心包积液,它可能会带来诊断和治疗方面的挑战。由于其与具有恶性潜能的组织有关联,因此有必要对肿瘤进行完整的手术切除。一名16日龄的新生儿被诊断为心包内未成熟畸胎瘤(IT),通过多学科团队方法成功进行了治疗,即迅速转诊以进行完整的手术切除,随后使用卡铂、依托泊苷和博来霉素(JEB)进行辅助化疗以预防复发。该婴儿目前正在密切随访中,监测血清甲胎蛋白(AFP)水平并进行影像学检查,以便早期诊断肿瘤复发和化疗相关并发症。