Ong John, Randhawa Rabinder
Department of Hepatology, Addenbrooke's Cambridge University Hospital, Cambridge, Cambridgeshire, UK.
BMJ Case Rep. 2014 Apr 11;2014:bcr2013009479. doi: 10.1136/bcr-2013-009479.
Vitamin C deficiency is rare in developed countries but there is an increased prevalence in chronic alcohol abusers. In the UK, it is common practice to treat patients with chronic alcoholism who are admitted to hospital with intravenous vitamins B1, B2, B3, B6 and C for 2-3 days, followed by oral thiamine and vitamin B-compound tablets. This is a case of a 57-year-old man with a history of chronic alcoholism and chronic obstructive lung disease who was admitted to the intensive care unit for pneumonia requiring ventilatory support. He was given high doses of intravenous vitamins B1, B2, B3, B6 and C for 3 days then oral thiamine and vitamin B compound tablets but developed scurvy 4 days later. He was restarted on oral vitamin C supplementation and showed signs of improvement within 3 days of treatment.
维生素C缺乏在发达国家较为罕见，但在慢性酒精滥用者中的患病率有所上升。在英国，对于因慢性酒精中毒入院的患者，常规做法是静脉注射维生素B1、B2、B3、B6和C 2至3天，随后口服硫胺素和复合维生素B片。这是一名57岁男性的病例，他有慢性酒精中毒和慢性阻塞性肺疾病史，因肺炎需要通气支持而入住重症监护病房。他接受了高剂量静脉注射维生素B1、B2、B3、B6和C 3天，然后口服硫胺素和复合维生素B片，但4天后患上了坏血病。他重新开始口服补充维生素C，治疗3天内即出现改善迹象。
