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脊髓空洞症合并抗利尿激素分泌异常。

Syringomyelia associated with inappropriate antidiuretic hormone secretion.

作者信息

Barros Alcalde Paula, González Quintela Arturo, Pena Seijo Marta, Pose-Reino Antonio

机构信息

Department of Internal Medicine, Complexo Hospitalario Universitario de Santiago de Compostela, Santiago de Compostela, La Coruña, Spain.

出版信息

BMJ Case Rep. 2014 Apr 11;2014:bcr2013202575. doi: 10.1136/bcr-2013-202575.

DOI:10.1136/bcr-2013-202575
PMID:24728892
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3987534/
Abstract

Hyponatraemia is the most common fluid-electrolyte disorder, and the most frequent related aetiologies are syndrome of inappropriate secretion of antidiuretic hormone (SIADH), which accounts for up to 38%. SIADH has been linked to multiple pathologies that affect the central nervous system; these disorders generally originate in the brain and, more rarely, in the spinal cord. It is often observed in patients undergoing neurosurgery and in patients with head injuries or intracranial tumours, and less common in those with spinal pathologies, especially traumatic. We describe an SIADH case associated with syringomyelia, in a patient admitted for severe, symptomatic hyponatraemia.

摘要

低钠血症是最常见的液体电解质紊乱,最常见的相关病因是抗利尿激素分泌不当综合征(SIADH),其占比高达38%。SIADH与多种影响中枢神经系统的病理状况有关;这些疾病通常起源于脑部,较少起源于脊髓。在接受神经外科手术的患者以及头部受伤或患有颅内肿瘤的患者中经常观察到,而在患有脊髓疾病(尤其是创伤性疾病)的患者中较少见。我们描述了一例与脊髓空洞症相关的SIADH病例,该患者因严重的症状性低钠血症入院。

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本文引用的文献

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Treatment of hyponatremia induced by the syndrome of Inappropriate antidiuretic hormone secretion: a multidisciplinary spanish algorithm.抗利尿激素分泌异常综合征所致低钠血症的治疗:一项多学科西班牙算法
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Incidence and pathophysiology of severe hyponatraemia in neurosurgical patients.神经外科患者严重低钠血症的发病率及病理生理学
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