Bell G R, Gurd A R, Orlowski J P, Andrish J T
J Bone Joint Surg Am. 1986 Jun;68(5):720-4.
Ten adolescent and preadolescent patients who underwent posterior spinal fusion for idiopathic scoliosis or spondylolisthesis were examined for the presence or absence of the postoperative syndrome of inappropriate antidiuretic-hormone secretion. For each patient, levels of serum sodium, serum osmolality, urine sodium, urine osmolality, and serum antidiuretic hormone were obtained preoperatively and postoperatively. The investigation clearly showed that the syndrome occurred in each patient, with the level of serum antidiuretic hormone being highest within a few hours postoperatively. This resulted in a reduction of urinary output, the reduction being maximum on the day of operation and the output gradually rising to normal over the next three days. This syndrome and its associated low postoperative urinary output is common after spinal fusion and should be treated with restriction of fluids rather than administration of increased amounts of fluid.
对10例因特发性脊柱侧凸或脊椎滑脱接受后路脊柱融合术的青少年及青春期前患者，检查是否存在术后抗利尿激素分泌不当综合征。对每位患者，术前及术后均测定血清钠、血清渗透压、尿钠、尿渗透压及血清抗利尿激素水平。调查清楚显示，每位患者均出现该综合征，血清抗利尿激素水平在术后数小时内最高。这导致尿量减少，减少量在手术当天最大，随后三天尿量逐渐恢复正常。该综合征及其相关的术后低尿量在脊柱融合术后很常见，应通过限制液体摄入而非增加液体量来治疗。
