Jiang Xiaoying, Jiang Yuehuang, Shi Guoyue, Zhou Tianshu
Department of Environmental Science and Shanghai Key Laboratory for Urban Ecology and Sustainability, Shanghai, P. R. China.
J Sep Sci. 2014 Jul;37(13):1671-8. doi: 10.1002/jssc.201301126. Epub 2014 May 11.
A graphene oxide-coated capillary was fabricated by using 3-aminopropyltriethoxysilane as the cross-linking agent. It was used for the separation and detection of three endocrine-disrupting chemicals, including bisphenol A, 4-nonylphenol, and 4-octylphenol by capillary electrochromatography. Due to the hydrophobicity, hydrogen bonding, and π-π interaction between graphene oxide and the analytes, the three analytes could be well separated in pH = 11.0, 20 mmol/L Na2 B4 O7 -NaOH/methanol mobile phase (50:50, v/v) within 950 s. After preconcentration, the detection limits were 6.7 × 10(-10) , 3.3 × 10(-9) , and 6.7 × 10(-10) mol/L (S/N = 3) for bisphenol A, nonylphenol, and octylphenol, respectively. The developed method was successfully applied to the determination of the above analytes in water samples. The satisfactory result demonstrated that the graphene oxide coated capillary used in capillary electrochromatography with amperometric detection was convenient to prepare, highly stable, and had good reproducibility.
以3-氨丙基三乙氧基硅烷为交联剂制备了氧化石墨烯涂层毛细管柱。将其用于毛细管电色谱法分离检测双酚A、4-壬基酚和4-辛基酚这三种内分泌干扰化学物质。由于氧化石墨烯与分析物之间存在疏水性、氢键和π-π相互作用，在pH = 11.0、20 mmol/L Na2B4O7-NaOH/甲醇流动相（50:50，v/v）中，950 s内可实现三种分析物的良好分离。富集后，双酚A、壬基酚和辛基酚的检测限分别为6.7×10(-10)、3.3×10(-9)和6.7×10(-10) mol/L（S/N = 3）。所建立的方法成功应用于水样中上述分析物的测定。令人满意的结果表明，用于安培检测的毛细管电色谱法中的氧化石墨烯涂层毛细管柱制备方便、稳定性高且重现性好。
