Safranek Jarmil, Geiger Jan, Vesely Vladimir, Vodicka Josef, Treska Vladislav
Department of Surgery, Charles University, Teaching Hospital, Plzen, Czech Republic.
Wideochir Inne Tech Maloinwazyjne. 2014 Mar;9(1):1-5. doi: 10.5114/wiitm.2014.40156. Epub 2014 Jan 25.
In spite of the progress in diagnosis and therapeutic options, esophageal perforation resulting in mediastinitis is a very serious condition with a high morbidity.
To evaluate the use of esophageal stents for the treatment of patients suffering from mediastinitis.
Retrospective (2008-2012) analysis of a group of patients requiring surgical treatment. The evaluation was focused on the cause of perforation, stent type and its parameters, the surgical method used, duration of stenting and total length of treatment.
In total, 16 patients were treated by stenting. All patients were treated with the stent being placed across the defect in the esophagus. Mediastinitis was accessed and drained with the aid of a thoracotomy or thoracolaparotomy (8 cases), or using a combination of a laparotomy/laparostomy and pleural drainage (5 cases). The most basic interventions were either pleural or external cervical drainage (3 and 1 cases, respectively). One patient, in whom a stricture had developed at the healed perforation, was subjected to esophageal resection. Four patients died. The average period that the stent was left in situ was 53.7 days. The average period of hospitalization of those patients who survived was 53.4 days.
Using stents in therapy neither increased survival (mortality of 25%), nor decreased the length of therapy of patients once mediastinitis had developed. The main advantage of stenting is the preservation of the native esophagus and the reduced extent of surgical mediastinal drainage.
尽管在诊断和治疗选择方面取得了进展,但导致纵隔炎的食管穿孔仍是一种非常严重的疾病,发病率很高。
评估食管支架在纵隔炎患者治疗中的应用。
对一组需要手术治疗的患者进行回顾性(2008 - 2012年)分析。评估重点在于穿孔原因、支架类型及其参数、所采用的手术方法、支架置入持续时间和总治疗时长。
共有16例患者接受了支架置入治疗。所有患者均通过将支架横跨食管缺损处放置进行治疗。借助开胸手术或胸腹联合手术(8例),或采用剖腹手术/剖腹造口术与胸腔引流相结合的方法(5例)对纵隔炎进行探查和引流。最基本的干预措施是胸腔或颈部外引流(分别为3例和1例)。1例在愈合的穿孔处出现狭窄的患者接受了食管切除术。4例患者死亡。支架平均留置时间为53.7天。存活患者的平均住院时间为53.4天。
一旦发生纵隔炎,使用支架进行治疗既未提高生存率(死亡率为25%),也未缩短患者的治疗时长。支架置入的主要优势在于保留了原生食管,并减少了纵隔手术引流的范围。