南非青少年纳入HIV疫苗试验。
Inclusion of South African adolescents in HIV vaccine trials.
作者信息
Adler David H
机构信息
Departments of Emergency Medicine and Community and Preventive Medicine, University of Rochester, Rochester, NY, USA.
出版信息
J AIDS HIV Res. 2012 Feb 1;4(2):30-35. doi: 10.5897/JAHR11.065.
Abstract
South Africa has more people living with HIV than any other nation. The HIV epidemic in South Africa is being driven by new infections among adolescents. Inclusion of adolescents in HIV vaccine trials is essential for successful vaccine development, however, recruitment and retention of at-risk South African adolescents into these trials poses a number of legal, ethical and operational challenges. This article discusses the South African ethico-legal context in which future adolescent HIV vaccine trials would be conducted followed by a review of available data regarding strategies for recruitment into these trials and retention of trial participants.
摘要
南非感染艾滋病毒的人数比其他任何国家都多。南非的艾滋病毒流行是由青少年中的新感染病例推动的。让青少年参与艾滋病毒疫苗试验对于疫苗的成功研发至关重要，然而，招募有风险的南非青少年参与这些试验并使其留在试验中面临一些法律、伦理和操作方面的挑战。本文讨论了未来开展青少年艾滋病毒疫苗试验的南非伦理法律背景，随后回顾了有关这些试验的招募策略和试验参与者留存情况的现有数据。
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