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波兰下西里西亚地区儿童持续性腹泻与不可分型肠致病性大肠杆菌(EPEC)菌株的关联。

Association of untypeable enteropathogenic Escherichia coli (EPEC) strains with persistent diarrhea in children from the region of lower Silesia in Poland.

出版信息

Pol J Microbiol. 2013;62(4):461-4.

Abstract

Enteropathogenic Escherichia coli strains (EPEC) carrying the eae gene encoding intimin are divided into typical strains producing bundle forming pili, encoded by the bfpA gene, and atypical strains lacking the gene. In the study typical and atypical EPEC that did not agglutinated with EPEC polyvalent antisera but carrying virulence factors characteristic to other pathogenic E. coli i.e. diffusely adhering and enteroaggregative E. coli were isolated from 24 (43.6%) of 55 children > 10 years old with persistent diarrhea. These results indicated that non-typeable typical and atypical EPEC can contribute to chronic intestinal infections in teenagers.

摘要

携带编码紧密素的 eae 基因的肠致病性大肠杆菌(EPEC)菌株分为产生束形成菌毛的典型菌株,由 bfpA 基因编码,以及缺乏该基因的非典型菌株。在这项研究中,从 55 名 10 岁以上持续性腹泻的儿童中分离出 24 株(43.6%)不与 EPEC 多价抗血清凝集但携带其他致病性大肠杆菌特征性毒力因子的典型和非典型 EPEC,即弥漫粘附性和肠聚集性大肠杆菌。这些结果表明,非定型的典型和非典型 EPEC 可导致青少年慢性肠道感染。

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