Ball M C, Dewberry T D, Freeman P G, Kemsley P D, Poe I
North Coast Livestock Health and Pest Authority, Lismore, New South Wales, Australia.
Aust Vet J. 2014 Jun;92(6):213-8. doi: 10.1111/avj.12170. Epub 2014 Apr 15.
Between 2006 and 2012, there were 11 horses diagnosed with Hendra virus (HeV) on 9 independent premises in New South Wales (NSW). We defined a case of HeV as premises where one or more horses were confirmed to be infected with HeV by PCR. All the cases occurred in the north-eastern region of NSW. In 8 of the 9 cases, infection occurred within 2 months over the winter of 2011. With no exception, the affected horses were kept at pasture on properties visited by flying foxes. Of the 11 horses testing positive for HeV, 5 had an association with a fence, with the horses dead or dying on a fence line. In the majority of cases, disease was an acute illness leading to death within 48 h. When signs of disease were observed, neurological signs predominated. There was limited spread to in-contact horses, with only two properties having more than one horse affected. There was significant variation in the sampling strategies undertaken by veterinarians.
Caution is needed to interpret a negative diagnosis when only swabs have been collected.
2006年至2012年期间，新南威尔士州（NSW）9个独立场所的11匹马被诊断感染亨德拉病毒（HeV）。我们将HeV病例定义为一个或多匹马经聚合酶链反应（PCR）确诊感染HeV的场所。所有病例均发生在新南威尔士州的东北部地区。9例中有8例感染发生在2011年冬季的2个月内。无一例外，受影响的马匹都饲养在狐蝠光顾过的牧场。在11匹HeV检测呈阳性的马中，5匹与围栏有关，这些马在围栏边死亡或濒死。在大多数病例中，疾病为急性疾病，导致在48小时内死亡。当观察到疾病迹象时，以神经症状为主。与接触马匹的传播有限，只有两个场所的马匹受影响不止一匹。兽医采取的采样策略存在显著差异。
仅采集拭子时，对阴性诊断的解读需谨慎。
